The city of Greensboro was officially founded in 1808, although some sources mention 1809. It received its name in honour of General Nathanael Greene, a hero of the American Revolutionary War, who commanded American troops at the Battle of Guilford Courthouse in 1781. Initially, the settlement, known as Greensborough until 1895, was planned as the new administrative centre of Guilford County. The decision to establish it was made for the convenience of residents, as the old county centre was not centrally located. A 42-acre plot of land was purchased for the new city from local resident Ralph Gorrell for 98 dollars.
Greensboro's growth was gradual but determined by several key factors. Geographical location: the city was deliberately placed in the geographical centre of Guilford County, which immediately defined its administrative significance. Transport: in the 19th century, Greensboro became a vital railway hub. By 1891, so many railway lines passed through the city in various directions that it earned the nickname "Gate City", symbolising its role as a gateway to the west and south of the country. Industry: the early development of textile manufacturing became the backbone of the city's economy. North Carolina's first steam-powered cotton mill began operations here as early as 1828.
In the first decades of its existence, Greensboro was a small settlement, which by 1829 had just over 500 inhabitants. The economy was centred around trade and the nascent textile industry. Education played a significant role in the city's cultural life. Thanks to the efforts of religious communities, particularly Quakers and Methodists, educational institutions were founded that still exist today, such as Guilford College (founded in 1837 as a boarding school) and Greensboro College. The presence of several colleges and universities significantly influenced the cultural climate and opportunities of the city.