The history of Várzea Grande, the second-largest city in the state of Mato Grosso, is inextricably linked to one of the most dramatic events in South American history — the Paraguayan War. The city was officially founded on May 15, 1867, at the height of this conflict (1864–1870), when the Brazilian province of Mato Grosso became a theater of operations. Initially, the settlement emerged as a military camp, with the primary task of serving as a support point and rear base for the provincial capital, Cuiabá, located on the opposite bank of the river.
Several key factors defined the city's establishment. Its name, which translates from Portuguese as "Large Floodplain," accurately describes its location on the vast and flat plain by the Cuiabá River. This level terrain was ideal for establishing a military camp. During the war years, Várzea Grande played an important strategic role, ensuring the security and supply of the capital. After the end of military operations, its geographical proximity to Cuiabá finally determined the city's fate: it transformed into an important agricultural and commercial adjunct, supplying the capital with food products.
Initially, the settlement's economy was entirely oriented toward military needs. After the war, the main activities became cattle ranching and agriculture. The fertile lands of the floodplain allowed for the cultivation of products for the rapidly growing market of neighboring Cuiabá. The cultural life of early Várzea Grande was shaped by its military past and the mix of settlers from different parts of Brazil who arrived here in search of land and new opportunities.