Unlike the ancient cities of Uzbekistan, whose history spans millennia, Fergana is a comparatively young city. Its emergence is directly linked to events of the 19th century, when the Fergana Valley became part of the Russian Empire. The city was founded in 1876 as a new military-administrative centre for the region. Initially, it was named New Margilan, as it was established just 12 kilometres from the ancient city of Margilan. In 1907, it was renamed Skobelev, and the city received its current name, Fergana, in 1924.
A key factor in Fergana's formation was its strategic location. The city was founded by the decision of military authorities to control the territory of the former Kokand Khanate. Unlike traditional Central Asian cities with their narrow and winding streets, Fergana was built according to a European model with a clear radial-ring layout. The central element was a military fortress, from which wide streets radiated like beams. Special attention was paid to landscaping: numerous parks and squares were laid out, thanks to which Fergana is still considered one of the greenest cities in the country today.
In the early stages, the city's economy and culture were defined by its status as an administrative and garrison centre. The first significant structures were the Governor's House, the Military Assembly, and other government buildings in the European style. Economic life was focused around the needs of the administration and the military. Gradually, with the development of cotton farming and industry in the fertile Fergana Valley, the city began to transform into an important industrial and cultural hub of the region.