The city of Santarém was officially founded on 22 June 1661. Its history is inextricably linked to the era of the colonization of Brazil. The settlement was established by Portuguese Jesuit missionaries on the site of a large village of the indigenous Tapajós people, who had inhabited these lands since ancient times. Initially, a mission operated here, becoming the core of the future city.
A key factor determining the development of Santarém was its unique geographic location. The city is situated at the confluence of two great rivers — the Amazon and the Tapajós, which transformed it into an important strategic and trading hub of the region. Control over this point ensured access to vast territories of the Amazon, facilitating both missionary activity and economic expansion.
The early economy of the city was closely tied to the natural resources of the surrounding jungles. In the 19th century, a powerful impulse for development was provided by the so-called rubber boom, which swept through the entire Amazon. Besides rubber extraction, logging played an important role. Culturally, Santarém became a place of synthesis between Portuguese traditions and indigenous beliefs. One of the striking manifestations of this heritage was the art of pottery making, examples of which can be seen in local museums today.