The history of the city of Nantong is closely linked to its unique geographical location in the Yangtze River Delta. The territory on which the city stands today was formed by river deposits that gradually created land from a small sandy island that existed during the Han Empire. The first significant settlements appeared here during the Tang Dynasty (618–907 AD), when the village of Jinghai was founded, where residents were engaged in salt evaporation. This marked the beginning of the region's economic specialization.
A key stage in the city's formation was the establishment of a military district in 958, which was soon transformed into the Tongzhou prefecture. Over the centuries, the status and administrative boundaries of the territory changed repeatedly, reflecting its growing importance. The city received its modern name—Nantong—in 1724. Its development was defined by two main factors: its advantageous location on the northern bank of the Yangtze, near its mouth at the East China Sea, and trade. The city became an important port and commercial hub for an agricultural region specializing in rice, cotton, and salt production.
Nantong's early economic and cultural characteristics largely determined its future destiny. Initially prospering through the salt industry, the city eventually became one of the largest centres of the textile industry in China. The first cotton mill was founded here as early as 1895. In the early 20th century, thanks to the efforts of local industrialist and philanthropist Zhang Jian, China's first public museum (1905) and the first teacher training institute were opened in Nantong, cementing the city's reputation as a cultural and educational centre.