The history of Pizhou is rooted in deep antiquity. According to historical records, as early as the time of the legendary Xia dynasty, the Pi fiefdom (邳国) existed in this territory. The first official administrative entity, Xiapi County (下邳县), was established here in 221 BC after the unification of China under the Qin dynasty. The settlement also played a significant role during the Zhou dynasty as the capital of the Pi vassal state.
A key factor in the city's emergence was its strategic geographical location. Situated on a fertile plain and along the route of the Grand Canal, Pizhou served as an important military, administrative, and commercial center for many centuries. Its status changed multiple times: during the Tang dynasty in 621, the Pizhou Prefecture was established, which was later restored during the Jin dynasty in 1129. It is this name, referring to the medieval administrative unit, that became permanently attached to the city.
Since ancient times, the region has been known for its developed agriculture, which defined its economic characteristics. Thanks to its location at the crossroads of trade routes, the city became an important center for the exchange of goods. Pizhou gained particular fame for the cultivation of grain crops and garlic. The city also entered history as the site of the famous Battle of Xiapi during the Three Kingdoms era, highlighting its strategic importance in the ancient and medieval history of the country.