The history of the modern city of Matamoros begins in the 18th century. In 1774, a group of thirteen settler families founded a settlement here, which was named San Juan de los Esteros Hermosos. Almost two decades later, in 1793, a Franciscan mission was established in the settlement, and it was renamed Villa del Refugio. The city received its current name in 1826 in honour of Mariano Matamoros, one of the heroes of the War of Independence of Mexico.
A key factor in the development of Matamoros was its strategic geographical location. The city is situated on the right bank of the Rio Grande, on the border with the United States and near the coast of the Gulf of Mexico. This facilitated its transformation into an important trade and transport hub. Its status as a port city and its proximity to the USA defined its economic growth, especially during periods when alternative trade routes were required. For example, during the American Civil War, Matamoros became a key centre for cotton exports.
Initially, the city's economy was focused on agriculture and livestock farming, but trade quickly came to the forefront. The period known as the "Golden Age of Cotton" attracted merchants from all over the world to Matamoros, contributing to the formation of a cosmopolitan atmosphere. This historical heritage, the blending of cultures, and its border location still define the unique character of the city today, making it an interesting destination for travellers wishing to explore the history and culture of northern Mexico.