Cheap flights to Santiago
9 cities have regular scheduled flights to Santiago (STI). 11 airlines fly to the city, from major international carriers to budget low-cost options. Most flights depart from New York City, Fort Lauderdale, Miami, Boston, Philadelphia. Compare fares, choose the best option and book your tickets online at the best price. Enter your departure city above to find flights and check prices.

San Juan — Panama City

New York City — Santiago


Orlando — Santiago

Fort Lauderdale — Santiago

Boston — Santiago

Panama City — Bogota


Philadelphia — Santiago
Popular departure cities to Santiago
Flight insights to Santiago
Data-driven trends for direct flights to Santiago — how often airlines fly, where passengers come from, and typical fares and flight times.
Most frequent departure cities
The most frequent direct routes to Santiago come from New York City, Fort Lauderdale and Miami. New York City leads with around 233 flights a week.
- New York City233 flights/week
- Fort Lauderdale34 flights/week
- Miami28 flights/week
- Boston28 flights/week
- Philadelphia14 flights/week
Top departure countries
Most direct flights to Santiago depart from United States, Puerto Rico and Panama. United States alone accounts for about 95% of all direct routes.
- United Statesavg $236
- Puerto Ricoavg $192
- Panamaavg $390
- Spainavg $551
Direct routes & fares
Popular non-stop routes to Santiago range from Boston at $151 to Fort Lauderdale at $367 — a quick way to compare direct-flight fares.
- New York Cityfrom $233
- Fort Lauderdalefrom $367
- Miamifrom $156
- Bostonfrom $151
- Philadelphiafrom $308
Cheapest departure cities
The cheapest places to fly to Santiago from right now are Boston from $151, Miami from $156 and San Juan from $192.
- Bostonfrom $151
- Miamifrom $156
- San Juanfrom $192
- Orlandofrom $199
- New York Cityfrom $233
Longest direct flights
The longest direct flight to Santiago is from Madrid at about 9h 6m, followed by Boston (3h 45m) and New York City (3h 33m).
- Madrid9h 6m
- Boston3h 45m
- New York City3h 33m
- Philadelphia3h 28m
- Panama City2h 25m
Frequently asked questions
- Which cities have flights to Santiago?
- There are 9+ cities with regular flights to Santiago, from major international hubs to nearby regional airports. Pick your departure city to compare fares and book.
- Where do most flights to Santiago depart from?
- Most travelers fly to Santiago from New York City, Fort Lauderdale, Miami, Boston, Philadelphia. These routes have the highest flight frequency and passenger traffic, so fares are usually competitive.
- How many airlines fly to Santiago?
- 11 airlines operate flights to Santiago, ranging from major international carriers to budget low-cost airlines. Competition helps keep fares affordable.
- When is the best time to book flights to Santiago?
- For short-haul routes, booking 4–8 weeks ahead usually gives the best prices. For long-haul flights, aim for 2–3 months ahead. Prices also drop in off-peak seasons and for midweek departures.
- How to find cheap flights to Santiago?
- Compare offers from multiple airlines, use flexible dates and set up price alerts. Our platform lets you track price trends and choose the best time to buy your tickets.