On this page, you can find and book flights from La Serena to Santiago. This domestic Chilean route covers a distance of 397 km, with around 39 flights operating weekly.
Direct flights are provided by LATAM, Sky Airline, and JetSmart. Ticket prices are dynamic; we recommend using the price chart and calendar to find the best deals. You can also find out in advance how to get to the airport of departure and how to travel from the airport to the city center.
The table shows direct flights La Serena → Santiago on the selected date. The flight takes approximately 1 h. Regular flights are operated by Latam Airlines Group, JetSmart and Sky Airline. Departures from La Florida Airport airports, arrivals at Arturo Merino Benitez Airport.
For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.
Below is a calendar of the lowest flight ticket prices for La Serena — Santiago by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $22 in r, and the most expensive are around $44 in J. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.
La Serena → Santiago, average one-way price
| Month | Average price | Level | Month | Average price | Level | Month | Average price | Level |
|---|---|---|---|---|---|---|---|---|
| Jan | $64 | high | May | $38 | low | Sep | $44 | medium |
| Feb | $61 | high | Jun | $45 | medium | Oct | $46 | medium |
| Mar | $41 | low | Jul | $60 | high | Nov | $49 | medium |
| Apr | $40 | low | Aug | $41 | low | Dec | $63 | high |
Some values are estimated based on seasonality.
The warmest weather in Santiago occurs in January and February, when temperatures rise to 27°C. June is the coldest and rainiest month, seeing peak precipitation of over 125 mm.
The lowest flight prices are recorded in June, starting $22. January is considered the most expensive month to travel, with ticket prices rising to $44.
November and March are the best times to fly, offering dry, comfortable weather and mid-range prices. It is best to avoid June due to the high likelihood of heavy rain.
Three airlines operate on this route: LATAM, Sky Airline, and JetSmart. Most flights are direct, keeping travel time between the cities to a minimum. With approximately 39 flights per week, there is plenty of flexibility when choosing your departure time. A full schedule and details for each carrier are provided in the list below.
Flights La Serena — Santiago depart from La Florida Airport and arrive at Arturo Merino Benitez Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.
The distance between the cities is about 397 km, so a direct flight takes on average 50 minutes to 1 hour.
LATAM, Sky Airline, and JetSmart operate regular flights on this route.
Yes, most flights on this route are direct, making it the fastest way to travel.
Airfares change constantly based on demand and booking date. You can check the current lowest price in the low-price calendar on this page.
Flights arrive at Santiago International Airport, also known as Arturo Merino Benítez International Airport (SCL).
Where travelers fly most — pick a route and check prices
