On this page, you can find and purchase flight tickets for the Santa Cruz de la Sierra — Panama City route. The total distance between the cities is 3,464 km, with a flight frequency of approximately 7 departures per week.
Flights on this route are operated by Copa Airlines (CM). Please note that ticket prices are dynamic, so we recommend using the low-price calendar and reviewing information on how to get to the departure airport and from the destination airport to the city center.
The table shows direct flights Santa Cruz de la Sierra → Panama City on the selected date. The flight takes approximately 4 h 52 min. Regular flights are operated by Copa Airlines. Departures from Viru Viru International Airport airports, arrivals at Tocumen International Airport and Marcos A. Gelabert International Airport.
For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.
Below is a calendar of the lowest flight ticket prices for Santa Cruz de la Sierra — Panama City by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from AED 1,752 in F, and the most expensive are around AED 2,045 in e. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.
Santa Cruz de la Sierra → Panama City, average one-way price
| Month | Average price | Level | Month | Average price | Level | Month | Average price | Level |
|---|---|---|---|---|---|---|---|---|
| Jan | AED 3,109 | high | May | AED 2,407 | medium | Sep | AED 2,307 | low |
| Feb | AED 2,959 | high | Jun | AED 2,608 | medium | Oct | AED 2,056 | low |
| Mar | AED 2,758 | medium | Jul | AED 2,858 | high | Nov | AED 2,507 | medium |
| Apr | AED 2,156 | low | Aug | AED 2,658 | medium | Dec | AED 3,109 | high |
Some values are estimated based on seasonality.
In Panama City, the highest air temperatures are observed in March and April, reaching 30.1°C. The wet season lasts from May to November, with the rainiest period falling in July and August when precipitation exceeds 300 mm per month.
The lowest flight cost is recorded for September, starting AED 1,751. Currently, the most expensive month to plan a trip is October, with ticket prices starting AED 2,045.
The best time to visit the city is considered to be February and March: these months see minimal rainfall and consistently warm weather. It is best to avoid the period from June to October due to peak humidity levels and frequent tropical downpours.
Regular air service on the Santa Cruz de la Sierra — Panama City route is provided by Copa Airlines (CM). The carrier operates about 7 direct flights per week, connecting Bolivia's largest city with Central America's main aviation hub. A detailed flight schedule and route options are available in the interactive list below.
Flights Santa Cruz de la Sierra — Panama City depart from Viru Viru International Airport and arrive at Tocumen International Airport and Marcos A. Gelabert International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.
A direct flight covers the distance of 3,464 km in approximately 4 hours and 10 minutes, depending on the specific flight and weather conditions.
The main carrier operating regular flights on this route is Copa Airlines (CM).
Yes, there is a direct air link between the cities, allowing for travel without additional layovers.
Flight prices change constantly depending on the season and flight occupancy; you can always find the current minimum in the low-price calendar on our page.
Most flights from Santa Cruz de la Sierra arrive at Panama City's Tocumen International Airport (PTY).
Where travelers fly most — pick a route and check prices
