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Cheap flights from Brussels to Santa Maria

Brussels
BRU
Samos
SMI

Flight deals from Brussels to Santa Maria

Below you can see the best deals on flights Brussels — Santa Maria for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 1 August, from $98.

Top 10 cheap flights from Brussels to Santa Maria

TB
$ 98

Brussels — Santa Maria

14:4519:25
8 Aug 2026
3 h 40 m
Direct flight
TB
$ 98

Brussels — Santa Maria

14:4519:25
1 Aug 2026
3 h 40 m
Direct flight
W4
W4
A3
$ 151

Brussels — Santa Maria

14:3018:00
18 Aug 2026
5 h 20 m
2 stops
W6
W6
A3
$ 159

Brussels — Santa Maria

09:3015:00
22 Aug 2026
5 h
2 stops
W6
W6
A3
$ 169

Brussels — Santa Maria

09:3015:00
22 Aug 2026
5 h
2 stops
W6
W6
A3
$ 171

Brussels — Santa Maria

09:3018:00
22 Aug 2026
4 h 55 m
2 stops
W6
A3
A3
$ 171

Brussels — Santa Maria

09:3018:00
18 Aug 2026
4 h 45 m
2 stops
SN
LX
LX
$ 172

Brussels — Santa Maria

16:2514:50
19 Aug 2026
8 h 15 m
2 stops
W4
A3
A3
$ 174

Brussels — Santa Maria

08:0507:30
17 Aug 2026
5 h 20 m
2 stops
W4
A3
A3
$ 174

Brussels — Santa Maria

08:0510:40
17 Aug 2026
5 h 10 m
2 stops

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Brussels — Santa Maria flight

On this page, you can find and book flights from Brussels to Santa Maria. This 10,498 km journey is operated on average once a week, so we recommend checking out how to get to Brussels Airport in advance.

Flights on this route are served by SN and TB airlines. Ticket prices are dynamic; to find the best deals, use the price chart and low-fare calendar available on this page, along with information on how to get from the arrival airport.

Flight ticket prices by day: Brussels — Santa Maria

Below is a calendar of the lowest flight ticket prices for Brussels — Santa Maria by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $98 in ,, and the most expensive are around $244 in y. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Brussels → Santa Maria, average one-way price

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$154lowMay$183mediumSep$211high
Feb$148lowJun$194mediumOct$183medium
Mar$165mediumJul$240highNov$154low
Apr$171mediumAug$245highDec$160low

Some values are estimated based on seasonality.

When to fly

The most comfortable weather in Santa Maria occurs in March, when up to 27 dry days are recorded. May is the hottest month, with temperatures reaching 33.4°C, while rainfall peaks in July and August, when it rains almost every day.

According to current data, the most budget-friendly flights are available in December, starting $210. Prices rise during the summer: for instance, a flight in July starts $267, and in August $216.

December is considered the optimal time for booking, combining low prices with relatively moderate rainfall. We recommend avoiding trips in mid-summer due to extreme humidity and a high risk of prolonged tropical rains.

Temperature · Santa Maria

Dry and wet days · Santa Maria

Wind speed and direction · Santa Maria

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How to get the best deal on a Brussels — Santa Maria ticket

  • Given the low flight frequency (only about once a week), book your tickets 2–3 months in advance to ensure availability for your preferred dates.
  • Use the low-fare calendar on this page to compare dates, as the price difference between nearby departures can exceed $64.
  • Compare fares from SN and TB: baggage allowance terms on such long-haul flights (over 10,000 km) can significantly impact the total value.
  • Monitor the price chart to catch a price drop when tickets are available at the minimum fare $210.

Airlines

Two airlines operate the route from Brussels to Santa Maria, with SN and TB being the primary carriers. Flights run approximately once a week, with most options involving connections at major transit hubs. You can view the detailed weekly schedule and choose the best option from the list below.

  • Brussels AirlinesSN
    1x/week
    WebsiteFleet: 468.3M pax/year
    • Direct flight BRU → SMI1x/week
      Duration
      3h 25m
      Days
      MTWTFSS
  • TUI fly BelgiumTB
    1x/week
    WebsiteFleet: 203.5M pax/year
    • Direct flight BRU → SMI1x/week
      Duration
      3h 40m
      Days
      MTWTFSS

Cities and airports on the Brussels — Santa Maria route

Flights Brussels — Santa Maria depart from Brussels Airport and Charleroi Brussels South Airport. Below are pages for the cities, countries, and airports on the route.

Departure airports

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Frequently asked questions about the Brussels — Santa Maria flight

How long is the flight from Brussels to Santa Maria?

The distance between the cities is 10,498 km. A direct flight would take approximately 12.5 hours; however, total travel time usually increases when factoring in connections.

Which airlines fly this route?

Regular service between the cities is provided by SN and TB. The current list of available flights and carriers for your dates is displayed at the top of the page.

Are there direct flights from Brussels to Santa Maria?

Currently, most flight options for this route involve layovers. Direct flights are rare, as the flight frequency is approximately once a week.

Which airport does the flight arrive at?

Flights arrive at Santa Maria Airport (SMI). Information on how to get from the airport to your accommodation can be found in the corresponding section of our website.

How can I buy the cheapest flight ticket?

Ticket prices change constantly based on demand. To find the best price, we recommend using the low-fare calendar and price chart provided on this page.

Where else you can fly from Brussels

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