Cheap flights to La Serena
6 cities have regular scheduled flights to La Serena (LSC). 3 airlines fly to the city, from major international carriers to budget low-cost options. Most flights depart from Santiago, Calama, Antofagasta, Concepción, Arica. Compare fares, choose the best option and book your tickets online at the best price. Enter your departure city above to find flights and check prices.

Concepción — La Serena

Calama — La Serena

Antofagasta — La Serena

Santiago — La Serena

Iquique — La Serena

Arica — La Serena
Popular departure cities to La Serena
Flight insights to La Serena
Data-driven trends for direct flights to La Serena — how often airlines fly, where passengers come from, and typical fares and flight times.
Most frequent departure cities
The most frequent direct routes to La Serena come from Santiago, Calama and Antofagasta. Santiago leads with around 111 flights a week.
- Santiago111 flights/week
- Calama35 flights/week
- Antofagasta34 flights/week
- Concepción4 flights/week
- Arica3 flights/week
Direct routes & fares
Popular non-stop routes to La Serena range from Santiago at $24 to Arica at $37 — a quick way to compare direct-flight fares.
- Santiagofrom $24
- Calamafrom $31
- Antofagastafrom $33
- Concepciónfrom $31
- Aricafrom $37
Cheapest departure cities
The cheapest places to fly to La Serena from right now are Santiago from $24, Calama from $31 and Concepción from $31.
- Santiagofrom $24
- Calamafrom $31
- Concepciónfrom $31
- Antofagastafrom $33
- Iquiquefrom $33
Longest direct flights
The longest direct flight to La Serena is from Arica at about 2h 8m, followed by Iquique (1h 53m) and Calama (1h 36m).
- Arica2h 8m
- Iquique1h 53m
- Calama1h 36m
- Concepción1h 30m
- Antofagasta1h 24m
Frequently asked questions
- Which cities have flights to La Serena?
- There are 6+ cities with regular flights to La Serena, from major international hubs to nearby regional airports. Pick your departure city to compare fares and book.
- Where do most flights to La Serena depart from?
- Most travelers fly to La Serena from Santiago, Calama, Antofagasta, Concepción, Arica. These routes have the highest flight frequency and passenger traffic, so fares are usually competitive.
- How many airlines fly to La Serena?
- 3 airlines operate flights to La Serena, ranging from major international carriers to budget low-cost airlines. Competition helps keep fares affordable.
- When is the best time to book flights to La Serena?
- For short-haul routes, booking 4–8 weeks ahead usually gives the best prices. For long-haul flights, aim for 2–3 months ahead. Prices also drop in off-peak seasons and for midweek departures.
- How to find cheap flights to La Serena?
- Compare offers from multiple airlines, use flexible dates and set up price alerts. Our platform lets you track price trends and choose the best time to buy your tickets.