Cheap flights to La Serena
For travelers planning a visit to this coastal region, the main arrival point is La Florida Airport, located just 5 km from the city. Air services connect La Serena with 6 cities, the most popular of which are routes from Santiago with a frequency of 111 flights per week, as well as from Calama (35 flights) and Antofagasta (34 flights). To better prepare for your trip, we recommend exploring the dedicated travel guide or the section on how to get there.
3 airlines operate regular flights to La Serena, with Latam Airlines Group and JetSmart playing a leading role. Sky Airline is also well-represented in the schedule, providing reliable connections with other provinces of Chile. Before your flight, it's worth checking the latest information in the weather block; below on the page, you will find detailed cards for departure cities with a convenient ticket search form.

Iquique — La Serena
Flight insights to La Serena
Data-driven trends for direct flights to La Serena — how often airlines fly, where passengers come from, and typical fares and flight times.
Most frequent departure cities
The most frequent direct routes to La Serena come from Santiago, Calama and Antofagasta. Santiago leads with around 111 flights a week.
- Santiago111 flights/week
- Calama35 flights/week
- Antofagasta34 flights/week
- Concepción4 flights/week
- Arica3 flights/week
Direct routes & fares
Popular non-stop routes to La Serena range from Santiago at $20 to Concepción at $49 — a quick way to compare direct-flight fares.
- Santiagofrom $20
- Calamafrom $27
- Antofagastafrom $32
- Concepciónfrom $49
- Aricafrom $43
Cheapest departure cities
The cheapest places to fly to La Serena from right now are Santiago from $20, Calama from $27 and Antofagasta from $32.
- Santiagofrom $20
- Calamafrom $27
- Antofagastafrom $32
- Aricafrom $43
- Iquiquefrom $45
Longest direct flights
The longest direct flight to La Serena is from Hanga Roa at about 5h 17m, followed by Punta Arenas (3h 49m) and Trujillo (3h 46m).
- Hanga Roa5h 17m
- Punta Arenas3h 49m
- Trujillo3h 46m
- Puerto Natales3h 37m
- El Calafate3h 25m
Popular departure cities to La Serena
Frequently asked questions
- How many cities offer flights to La Serena?
- Currently, flights to La Serena are available from 6 different cities. Most routes connect this region with key transport hubs in Chile, ensuring a steady flow of passengers.
- Which cities have the most frequent flights to La Serena?
- The highest number of flights arrives from Santiago — 111 weekly departures. Other popular departure points include Calama (35 flights per week), Antofagasta (34 flights), and Concepción (4 flights).
- How many airlines fly to La Serena?
- 3 airlines operate flights on this route. The main carriers providing the majority of the traffic are Latam Airlines Group, JetSmart, and Sky Airline.
- Which airports receive flights to La Serena?
- All passenger flights are handled by La Florida Airport (LSC). The airport is conveniently located just 5 kilometers from the center of La Serena, allowing for a quick trip to the city after landing.
- How to find cheap tickets to La Serena?
- To find the best fares, we recommend using the search form on this page and comparing offers from different airlines. Typically, lower prices are available when booking several months in advance or by choosing mid-week departures.