Cheap flights from Antofagasta
Antofagasta is served by Cerro Moreno International Airport, located 23 kilometers from the city limits. From here, travelers can access several key routes connecting northern Chile with other parts of the country and neighboring nations. The busiest destination is Santiago, with 247 weekly flights, while flights to La Serena, Concepción, Lima, and Cali are also in high demand.
Three airlines operate regular services from the city, with the majority of flights provided by Latam Airlines Group, JetSmart, and Sky Airline. To make trip planning easier, we have provided city cards below with interest-based filters to help you choose the right destination. You can find more information about your destination in our travel guide or check the current weather in the region.

Antofagasta — La Serena

Antofagasta — Concepción

Antofagasta — Santiago

Antofagasta — Cali

Antofagasta — Lima
Flight insights from Antofagasta
Data-driven trends for direct flights from Antofagasta — how often airlines fly, where they go, and typical fares and flight times.
Most frequent destinations
The most frequent direct destinations from Antofagasta are Santiago, La Serena and Concepción. Santiago leads with around 247 flights a week.
- Santiago247 flights/week
- La Serena34 flights/week
- Concepción25 flights/week
- Lima6 flights/week
- Cali2 flights/week
Top countries
Most direct flights from Antofagasta head to Chile, Peru and Colombia. Chile alone accounts for about 97% of all direct routes.
- Chileavg $33
- Peruavg $168
- Colombiaavg $136
Direct routes & fares
Popular non-stop routes from Antofagasta range from Santiago at $30 to Lima at $168 — a quick way to compare direct-flight fares.
- Santiagofrom $30
- La Serenafrom $34
- Concepciónfrom $35
- Limafrom $168
- Califrom $136
Cheapest destinations
The cheapest destinations from Antofagasta right now are Santiago from $30, La Serena from $34 and Concepción from $35.
- Santiagofrom $30
- La Serenafrom $34
- Concepciónfrom $35
- Califrom $136
- Cuscofrom $156
Longest direct flights
The longest direct flight from Antofagasta is to Paris at about 14h 19m, followed by London (14h 18m) and New York City (9h 39m).
- Paris14h 19m
- London14h 18m
- New York City9h 39m
- Orlando8h 3m
- Miami7h 38m
Popular destinations from Antofagasta
Frequently asked questions
- Which airports serve Antofagasta?
- The city's main aviation hub is Cerro Moreno International Airport (ANF). It is located approximately 23 kilometers from the center of Antofagasta and handles both domestic and international flights.
- How many destinations are available from Antofagasta?
- Currently, there are 5 main destinations reachable from the city. Most routes connect Antofagasta with key Chilean cities, as well as important transport hubs in Peru and Colombia.
- What are the most popular destinations from Antofagasta?
- The highest demand is for flights to Santiago (247 flights per week), La Serena (34 flights), and Concepción (25 flights). Regular flights are also operated to Lima and Cali.
- How many airlines fly from Antofagasta?
- Three airlines operate scheduled flights from the local airport. The largest carriers, providing the bulk of the traffic, are Latam Airlines Group, JetSmart, and Sky Airline.
- How can I find cheap flights from Antofagasta?
- To find the best deals, we recommend booking your tickets in advance and using the filters on our page to compare available options. It is also worth looking into low-cost carriers, which often offer competitive fares on popular domestic routes.