Cheap flights from La Serena to Antofagasta

La Florida
LSC
Cerro Moreno
ANF

Flight deals from La Serena to Antofagasta

Below you can see the best deals on flights La Serena — Antofagasta for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 26 August, from $34.

Top 10 cheap flights from La Serena to Antofagasta

JA
$ 33

La Serena — Antofagasta

19:07—20:29
26 Aug 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

17:52—19:14
10 Sep 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

09:26—10:48
10 Sep 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

18:28—19:50
2 Sep 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

12:47—14:09
28 Aug 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

18:38—20:00
3 Sep 2026
1 h 22 m
Direct flight
JA
$ 33

La Serena — Antofagasta

20:31—21:53
4 Sep 2026
1 h 22 m
Direct flight
JA
$ 42

La Serena — Antofagasta

18:28—19:50
27 Aug 2026
1 h 22 m
Direct flight
JA
$ 49

La Serena — Antofagasta

16:23—17:45
9 Sep 2026
1 h 22 m
Direct flight
JA
$ 49

La Serena — Antofagasta

19:07—20:29
19 Aug 2026
1 h 22 m
Direct flight

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the La Serena — Antofagasta flight

Looking for cheap flights from La Serena to Antofagasta? Compare fares from different airlines, check the flight schedule and travel time — and book your La Serena — Antofagasta ticket online at the best price.

The route has direct flights — around 29 flights per week, flights are operated by Latam Airlines Group, JetSmart, Sky Airline, a nonstop flight takes about 3 h 58 min, the distance between the cities is around 698 km.

Planning your trip? You may find our Antofagasta travel guide, how to get from the airport into town and Antofagasta weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $33Min. price
OctoberCheapest
AprilPeak season
YesDirect flights
698 kmDistance
3 h 58 minTravel time
3Airlines
29 / wkFlights

Flight schedule from La Serena to Antofagasta

The table shows direct flights from La Serena to Antofagasta on the selected date. The flight takes approximately 3 h 58 min. Regular flights are operated by Latam Airlines Group, JetSmart and Sky Airline. Departures from La Florida Airport airports, arrivals at Cerro Moreno International Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 14 Aug 2026

Flight ticket prices by day: La Serena — Antofagasta

Below is a calendar of the lowest flight ticket prices for La Serena — Antofagasta by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $33 in October, and the most expensive are around $56 in April. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from La Serena to Antofagasta by month. Tickets are usually cheapest in June (around $58) and priciest in January (about $84) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$84highMay$60lowSep$74high
Feb$82highJun$58lowOct$67medium
Mar$72mediumJul$78highNov$70medium
Apr$66mediumAug$62lowDec$83high

Some values are estimated based on seasonality.

When to fly

Weather in Antofagasta: it is warmest in February (up to 25 °C on average) and coolest in July (around 19 °C). The driest month is January.

Tickets are usually cheapest in October and most expensive in April. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Antofagasta

Dry and wet days · Antofagasta

Wind speed and direction · Antofagasta

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How to get the best deal on a La Serena — Antofagasta ticket

  • Book ahead: fares for La Serena — Antofagasta are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Flights La Serena — Antofagasta operate on Sundays, Mondays, Tuesdays, Wednesdays, Thursdays and Fridays — keep that in mind when picking your travel dates.
  • The cheapest month to fly to Antofagasta is usually October — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the La Serena — Antofagasta route are operated by 3 airlines; Latam Airlines Group runs the most flights (around 48% of all flights). Compare carriers, flight shares and schedules below.

  • Latam Airlines GroupLA
    5x/week
    WebsiteFleet: 34782M pax/year
    • Direct flight LSC → ANF5x/week
      Duration
      1h 21m
      Days
      MTWTFSS
    48.3%Open →
  • JetSmartJA
    4x/week
    WebsiteFleet: 328.2M pax/year
    • Direct flight LSC → ANF4x/week
      Duration
      1h 22m
      Days
      MTWTFSS
    37.9%Open →
  • Sky AirlineH2
    1x/week
    WebsiteFleet: 368.7M pax/year
    • Direct flight LSC → ANF1x/week
    13.8%Open →

Cities and airports on the La Serena — Antofagasta route

Flights La Serena — Antofagasta depart from La Florida Airport and arrive at Cerro Moreno International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

La Serena

LSC
Chile
About the cityHow to get thereWeatherAll about the country Chile
Arrival

Antofagasta

ANF
Chile
About the cityHow to get thereWeatherAll about the country Chile
Departure airports
Arrival airports

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Frequently asked questions about the La Serena — Antofagasta flight

How long is the flight from La Serena to Antofagasta?

A nonstop La Serena — Antofagasta flight takes about 3 h 58 min — the distance between the cities is around 698 km.

How far is it from La Serena to Antofagasta?

The distance from La Serena to Antofagasta is about 698 km, which a nonstop flight covers in around 3 h 58 min.

Are there direct flights from La Serena to Antofagasta?

Yes, there are nonstop flights La Serena — Antofagasta — around 29 flights per week.

Which airlines fly from La Serena to Antofagasta?

Airlines operating La Serena — Antofagasta include Latam Airlines Group, JetSmart, Sky Airline. See the full list with schedules in the "Airlines" section on this page.

Which airports do La Serena — Antofagasta flights use?

Flights from La Serena depart from La Florida Airport, and arrive at Cerro Moreno International Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from La Serena to Antofagasta?

The price of a La Serena — Antofagasta ticket depends on your travel date, season and demand: it is usually cheapest to fly in October, and most expensive in April. Tickets typically cost between $33 and $56. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights La Serena — Antofagasta?

Flights La Serena — Antofagasta are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is October. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from La Serena to Antofagasta?

To catch a low fare La Serena — Antofagasta, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually October.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from La Serena

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Where else you can fly from Antofagasta

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SantiagoConcepciónLimaCali

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