Cheap flights from Santiago
The primary aviation hub of the Chilean capital is Arturo Merino Benitez Airport, located just 12 kilometers from the city center. An extensive route network connects Santiago with dozens of cities worldwide, providing reliable service to key regional centers. Flights to Buenos Aires (311 departures per week) are in the highest demand, along with domestic routes such as Calama and Antofagasta, each seeing over 270 flights weekly.
Flights from Chile's capital are provided by 23 airlines, with Latam Airlines Group, Sky Airline, and JetSmart holding leading positions in terms of passenger volume. Thanks to the high frequency of departures, passengers have access to a wide selection of fares and convenient connection options. Below on this page, you will find city cards with handy filters to help you navigate destinations and choose the best option for your upcoming trip.

Santiago — La Serena

Santiago — Concepción

Santiago — Mendoza

Santiago — Temuco

Santiago — Antofagasta

Santiago — Calama

Santiago — Puerto Montt

Santiago — Copiapo

Santiago — Valdivia

Santiago — Iquique

Santiago — Buenos Aires

Santiago — Osorno
Flight insights from Santiago
Data-driven trends for direct flights from Santiago — how often airlines fly, where they go, and typical fares and flight times.
Most frequent destinations
The most frequent direct destinations from Santiago are Buenos Aires, Calama and Antofagasta. Buenos Aires leads with around 311 flights a week.
- Buenos Aires311 flights/week
- Calama289 flights/week
- Antofagasta279 flights/week
- Lima261 flights/week
- Sao Paulo258 flights/week
Top countries
Most direct flights from Santiago head to Chile, Brazil and Argentina. Chile alone accounts for about 45% of all direct routes.
- Chileavg $74
- Brazilavg $155
- Argentinaavg $84
- Peruavg $118
- United Statesavg $346
Direct routes & fares
Popular non-stop routes from Santiago range from Antofagasta at $27 to Sao Paulo at $141 — a quick way to compare direct-flight fares.
- Buenos Airesfrom $51
- Calamafrom $34
- Antofagastafrom $27
- Limafrom $99
- Sao Paulofrom $141
Cheapest destinations
The cheapest destinations from Santiago right now are La Serena from $22, Antofagasta from $27 and Concepción from $27.
- La Serenafrom $22
- Antofagastafrom $27
- Concepciónfrom $27
- Osornofrom $30
- Copiapofrom $31
Popular destinations from Santiago
Frequently asked questions
- Which airports serve Santiago?
- The city's main aviation hub is Arturo Merino Benitez International Airport (SCL). It is located 12 kilometers from the central part of the capital and handles flights from all the region's major airlines.
- How many airlines operate flights from Santiago?
- Currently, 23 airlines provide air service from the Chilean capital. Among the largest carriers are Latam Airlines Group, Sky Airline, and JetSmart, which offer the most extensive flight networks for both domestic and international routes.
- What are the most popular destinations from Santiago?
- The highest number of flights from Santiago Airport are to Buenos Aires (311 flights per week) and Lima (261 flights). Among domestic routes, Calama (289 flights) and Antofagasta (279 flights) lead the way, connecting the capital with the country's northern regions.
- Are there direct flights from Santiago to Europe?
- Yes, there are regular direct flights from the capital of Chile to Europe, specifically to Madrid. Approximately 80 flights per week operate on this route, making Spain an important "gateway" for travelers from South America.
- How can I find cheap flights from Santiago?
- To find the best deals, we recommend checking flights from budget carriers such as Sky Airline and JetSmart, which often offer competitive fares. It is also worth looking for tickets to popular Latin American destinations like São Paulo or Bogotá, where high flight frequency helps keep prices flexible.
- Which international destinations are available within South America?
- Santiago has intensive connections to key cities across the continent: in addition to Buenos Aires and Lima, popular routes include São Paulo (258 flights per week), Rio de Janeiro (109 flights), and Bogotá (95 flights).