Cheap flights from Santiago to Guayaquil

Arturo Merino Benítez
SCL
José Joaquín de Olmedo
GYE

Flight deals from Santiago to Guayaquil

Below you can see the best deals on flights Santiago — Guayaquil for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 20 September, from $216.

Top 10 cheap flights from Santiago to Guayaquil

LA
LA
$ 229

Santiago — Guayaquil

18:45—01:45
3 Sep 2026
8 h
1 stop
LA
LA
$ 229

Santiago — Guayaquil

05:40—14:45
3 Sep 2026
10 h 5 m
1 stop
LA
LA
$ 229

Santiago — Guayaquil

18:45—01:45
5 Sep 2026
8 h
1 stop
LA
LA
$ 229

Santiago — Guayaquil

06:40—14:45
9 Sep 2026
10 h 5 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

06:40—14:35
30 Aug 2026
8 h 55 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

06:40—17:35
30 Aug 2026
11 h 55 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

06:40—14:35
26 Aug 2026
8 h 55 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

15:20—23:30
26 Aug 2026
9 h 10 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

06:40—17:35
26 Aug 2026
11 h 55 m
1 stop
AV
AV
$ 242

Santiago — Guayaquil

06:40—23:30
26 Aug 2026
17 h 50 m
1 stop

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Santiago — Guayaquil flight

Looking for cheap flights from Santiago to Guayaquil? Compare fares from different airlines, check the flight schedule and travel time — and book your Santiago — Guayaquil ticket online at the best price.

The route has direct flights — around 14 flights per week, flights are operated by Latam Airlines Group, a nonstop flight takes about 5 h 18 min, the distance between the cities is around 3,592 km.

Planning your trip? You may find our Guayaquil travel guide, how to get from the airport into town and Guayaquil weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $212Min. price
NovemberCheapest
MarchPeak season
YesDirect flights
3,592 kmDistance
5 h 18 minTravel time
1Airlines
14 / wkFlights

Flight schedule from Santiago to Guayaquil

The table shows direct flights from Santiago to Guayaquil on the selected date. The flight takes approximately 5 h 18 min. Regular flights are operated by Latam Airlines Group. Departures from Arturo Merino Benitez Airport airports, arrivals at Jose Joaquin de Olmedo Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 14 Aug 2026

Flight ticket prices by day: Santiago — Guayaquil

Below is a calendar of the lowest flight ticket prices for Santiago — Guayaquil by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $212 in November, and the most expensive are around $270 in March. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--
--

Prices by month

Average one-way fares from Santiago to Guayaquil by month. Tickets are usually cheapest in October (around $290) and priciest in December (about $411) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$387highMay$302lowSep$302low
Feb$350mediumJun$302lowOct$290low
Mar$326mediumJul$375highNov$290low
Apr$326mediumAug$326mediumDec$411high

Some values are estimated based on seasonality.

When to fly

Weather in Guayaquil: it is warmest in December (up to 30 °C on average) and coolest in June (around 28 °C). The driest month is November.

Tickets are usually cheapest in November and most expensive in March. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Guayaquil

Dry and wet days · Guayaquil

Wind speed and direction · Guayaquil

We'll let you know if you need a visa

Enter your destination or
Your nationality
Destination

How to get the best deal on a Santiago — Guayaquil ticket

  • Book ahead: fares for Santiago — Guayaquil are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • The cheapest month to fly to Guayaquil is usually November — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Santiago — Guayaquil route are operated by 1 airline; Latam Airlines Group runs the most flights (around 100% of all flights). Compare carriers, flight shares and schedules below.

  • Latam Airlines GroupLA
    5x/week
    WebsiteFleet: 34782M pax/year
    • Direct flight SCL → GYE5x/week
      Duration
      5h 18m
      Days
      MTWTFSS
    100.0%Open →

Cities and airports on the Santiago — Guayaquil route

Flights Santiago — Guayaquil depart from Arturo Merino Benitez Airport and arrive at Jose Joaquin de Olmedo Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Santiago

SCL
Chile
About the cityHow to get thereWeatherAll about the country Chile
Arrival

Guayaquil

GYE
Ecuador
About the cityHow to get thereWeatherAll about the country Ecuador
Departure airports
Arrival airports

Interesting articles about Guayaquil

Free Public Transport AbroadUseful information

Free Public Transport Abroad

How to get around abroad is always a tricky question. Some simply buy a day pass and spare no expense, while others prefer to walk to avoid spending extra money on “it’s only a ten-minute walk!”. But…

The World’s Largest CitiesInteresting

The World’s Largest Cities

If you prefer non-stop action to quiet solitude somewhere by the sea or in the mountains—this article is for you. We’ve already told you about the oldest cities in the world, and now it’s time to delv…

Interesting

Most Dangerous Countries for Travel

International SOS assessed health and life risks for travelers in various countries worldwide and created an interactive map. Based on data from the British company Ipsos Mori, International SOS asses…

Interesting

Top Cosmodrome Tours

USA Cape Canaveral and Kennedy Space Center The Kennedy Space Center is one of the world’s main spaceports. A rocket park and a museum complex with space attractions are open to visitors, however, mos…

Backpacking Through Latin AmericaInteresting

Backpacking Through Latin America

Latin America is a “mystical” milestone in world culture. Latin America is a place hidden from the all-seeing eye of news feeds and emergency reports from CNN. A place where eternity is captured in th…

The Most Dangerous Areas in the World: Where Tourists Should Not GoTips for Travelers

The Most Dangerous Areas in the World: Where Tourists Should Not Go

The world is too vast to limit oneself to “all-inclusive” hotels, but sometimes the thirst for adventure leads travelers to places where travel insurance turns into a useless piece of paper. There are…

Frequently asked questions about the Santiago — Guayaquil flight

How long is the flight from Santiago to Guayaquil?

A nonstop Santiago — Guayaquil flight takes about 5 h 18 min — the distance between the cities is around 3,592 km.

How far is it from Santiago to Guayaquil?

The distance from Santiago to Guayaquil is about 3,592 km, which a nonstop flight covers in around 5 h 18 min.

Are there direct flights from Santiago to Guayaquil?

Yes, there are nonstop flights Santiago — Guayaquil — around 14 flights per week.

Which airlines fly from Santiago to Guayaquil?

Airlines operating Santiago — Guayaquil include Latam Airlines Group. See the full list with schedules in the "Airlines" section on this page.

Which airports do Santiago — Guayaquil flights use?

Flights from Santiago depart from Arturo Merino Benitez Airport, and arrive at Jose Joaquin de Olmedo Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Santiago to Guayaquil?

The price of a Santiago — Guayaquil ticket depends on your travel date, season and demand: it is usually cheapest to fly in November, and most expensive in March. Tickets typically cost between $212 and $270. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Santiago — Guayaquil?

Flights Santiago — Guayaquil are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is November. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Santiago to Guayaquil?

To catch a low fare Santiago — Guayaquil, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually November.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from Santiago

See all
Buenos AiresCalamaAntofagastaLimaSao PauloConcepciónPuerto MonttLa SerenaRio de JaneiroIquiqueBogotaCopiapoPunta ArenasPanama CityMadridFlorianopolisAricaTemucoMendozaMiamiBalmacedaMontevideoMexico CityHanga RoaSydneyOsornoHoustonBarilocheCuscoBelo HorizonteBrasiliaDallasAtlantaLos AngelesTorontoNew York CityCordobaParisBarcelonaMelbourne

Where else you can fly from Guayaquil

See all
QuitoBogotaPanama CityNew York CityMiamiLimaMadridPuerto AyoraFort LauderdaleMedellínCuencaSan SalvadorBuenos AiresSan CristobalSan JoséAmsterdam

We use cookies and services to collect user information. This is essential for the functioning of the site and for marketing purposes. You can find out more in .