Cheap flights from Panama City
Panama City is served by two main air hubs: Tocumen International Airport, located 18 kilometers from the center, and Marcos A. Gelabert Airport, which is just 4 kilometers away. The air network covers an extensive range of cities, offering travelers dozens of popular routes across the continent. Among the most sought-after destinations are regular flights to Bogota with a frequency of 192 departures per week, Medellin (148 flights), and San José (147 flights).
In total, 22 airlines operate from Panama's capital, ensuring high accessibility for international tourists. The largest carrier is Copa Airlines, which operates more than 3,000 flights weekly; Avianca and United Airlines also hold significant market shares. Below on this page, you will find city cards with interest filters to help you navigate the route network and choose the destination for your next journey.
Panama City — David
Panama City — Medellín
Panama City — San José
Panama City — Guatemala City
Panama City — San Salvador
Panama City — Cali
Panama City — Santa Marta
Panama City — Cartagena
Panama City — Bocas del Toro
Panama City — Cúcuta
Panama City — Bogota
Panama City — San Andres
Flight insights from Panama City
Data-driven trends for direct flights from Panama City — how often airlines fly, where they go, and typical fares and flight times.
Most frequent destinations
The most frequent direct destinations from Panama City are Bogota, Medellín and San José. Bogota leads with around 192 flights a week.
- Bogota192 flights/week
- Medellín148 flights/week
- San José147 flights/week
- Miami124 flights/week
- Punta Cana114 flights/week
Top countries
Most direct flights from Panama City head to United States, Colombia and Mexico. United States alone accounts for about 20% of all direct routes.
- United Statesavg $317
- Colombiaavg $161
- Mexicoavg $248
- Dominican Republicavg $279
- Argentinaavg $377
Direct routes & fares
Popular non-stop routes from Panama City range from Medellín at $143 to Miami at $316 — a quick way to compare direct-flight fares.
- Bogotafrom $188
- Medellínfrom $143
- San Joséfrom $147
- Miamifrom $316
- Punta Canafrom $269
Cheapest destinations
The cheapest destinations from Panama City right now are David from $74, Medellín from $143 and Quito from $144.
Longest direct flights
The longest direct flight from Panama City is to Amsterdam at about 11h 50m, followed by Paris (11h 37m) and Madrid (10h 58m).
- Amsterdam11h 50m
- Paris11h 37m
- Madrid10h 58m
- Montevideo7h 29m
- San Francisco7h 21m
Popular destinations from Panama City
Colombia
Colombia
Costa Rica
United States
Dominican Republic
Mexico
United States
Peru
United States
Mexico
Ecuador
Argentina
Chile
Ecuador
Guatemala
Brazil
Dominican Republic
El Salvador
Argentina
Colombia
Colombia
United States
United States
United States
Cuba
Venezuela
Panama
United States
Uruguay
Brazil
Paraguay
Nicaragua
Puerto Rico
Canada
Curacao
Honduras
United States
Aruba
Spain
Colombia
Panama
United States
Colombia
United States
United States
France
Trinidad and Tobago
Honduras
Bolivia
Mexico
Argentina
Guyana
Mexico
Brazil
Venezuela
Netherlands
Brazil
United States
Jamaica
BrazilFrequently asked questions
- Which airports serve Panama City?
- Passenger flights operate from two main air hubs: the primary international hub, Tocumen (PTY), located 18 km from the city, and Marcos A. Gelabert Airport (PAC), situated just 4 km from the center and focusing on regional flights.
- How many airlines fly from Panama City?
- Currently, 22 airlines provide air connections from the city. The leader in departures is the flagship carrier Copa Airlines, while Avianca, United Airlines, and Euroairlines also maintain an active presence in the region.
- What are the most popular destinations from Panama City?
- The highest number of weekly flights from Panama City are to Bogota (192), Medellin (148), and San José (147). Other top routes include Miami, Punta Cana, and Mexico City, ensuring connections with key cities across the Americas.
- Which destinations from Panama City are popular for beach holidays?
- For a coastal getaway, travelers most often choose direct flights to Punta Cana (114 flights per week) or Cancun in Mexico (85 flights). These resorts lead in flight frequency among all beach destinations available from the Panamanian capital.
- How can I find the best flight deals from Panama City?
- To find the best flight options, we recommend using the city cards with interest filters provided on this page. This will help you quickly compare offers from 22 airlines and select the perfect route from the many available destinations.