Cheap flights from Medellín to Panama City

José María Córdova
MDE
Tocumen
PTY

Flight deals from Medellín to Panama City

Below you can see the best deals on flights Medellín — Panama City for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 13 October, from $174.

Top 10 cheap flights from Medellín to Panama City

CM
$ 186

Medellín — Panama City

10:35—12:04
8 Sep 2026
1 h 29 m
Direct flight
CM
$ 186

Medellín — Panama City

05:00—06:27
29 Aug 2026
1 h 27 m
Direct flight
CM
$ 186

Medellín — Panama City

08:35—10:02
29 Aug 2026
1 h 27 m
Direct flight
CM
$ 186

Medellín — Panama City

09:15—10:42
29 Aug 2026
1 h 27 m
Direct flight
CM
$ 186

Medellín — Panama City

10:35—12:02
29 Aug 2026
1 h 27 m
Direct flight
CM
$ 186

Medellín — Panama City

10:35—12:04
9 Sep 2026
1 h 29 m
Direct flight
CM
$ 186

Medellín — Panama City

18:20—19:49
4 Sep 2026
1 h 29 m
Direct flight
CM
$ 186

Medellín — Panama City

12:40—14:09
4 Sep 2026
1 h 29 m
Direct flight
CM
$ 186

Medellín — Panama City

09:15—10:44
4 Sep 2026
1 h 29 m
Direct flight
CM
$ 186

Medellín — Panama City

16:30—17:59
3 Sep 2026
1 h 29 m
Direct flight

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Medellín — Panama City flight

Looking for cheap flights from Medellín to Panama City? Compare fares from different airlines, check the flight schedule and travel time — and book your Medellín — Panama City ticket online at the best price.

The route has direct flights — around 147 flights per week, flights are operated by Copa Airlines, a nonstop flight takes about 1 h 26 min, the distance between the cities is around 531 km.

Planning your trip? You may find our Panama City travel guide, how to get from the airport into town and Panama City weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $164Min. price
MarchCheapest
NovemberPeak season
YesDirect flights
531 kmDistance
1 h 26 minTravel time
1Airlines
147 / wkFlights

Flight schedule from Medellín to Panama City

The table shows direct flights from Medellín to Panama City on the selected date. The flight takes approximately 1 h 26 min. Regular flights are operated by Copa Airlines. Departures from Jose Maria Cordova International Airport and Enrique Olaya Herrera Airport airports, arrivals at Tocumen International Airport and Marcos A. Gelabert International Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 14 Aug 2026

Flight ticket prices by day: Medellín — Panama City

Below is a calendar of the lowest flight ticket prices for Medellín — Panama City by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $164 in March, and the most expensive are around $186 in November. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Medellín to Panama City by month. Tickets are usually cheapest in September (around $205) and priciest in December (about $308) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$296highMay$217lowSep$205low
Feb$262mediumJun$251mediumOct$205low
Mar$285highJul$285highNov$239medium
Apr$274highAug$262mediumDec$308high

Some values are estimated based on seasonality.

When to fly

Weather in Panama City: it is warmest in March (up to 30 °C on average) and coolest in November (around 28 °C). The driest month is February.

Tickets are usually cheapest in March and most expensive in November. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Panama City

Dry and wet days · Panama City

Wind speed and direction · Panama City

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How to get the best deal on a Medellín — Panama City ticket

  • Book ahead: fares for Medellín — Panama City are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Medellín is served by more than one airport — compare fares and travel time to each before you book.
  • The cheapest month to fly to Panama City is usually March — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Medellín — Panama City route are operated by 1 airline; Copa Airlines runs the most flights (around 100% of all flights). Compare carriers, flight shares and schedules below.

  • Copa AirlinesCM
    49x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight MDE → PTY49x/week
      Duration
      1h 27m
      Days
      MTWTFSS
    100.0%Open →

Cities and airports on the Medellín — Panama City route

Flights Medellín — Panama City depart from Jose Maria Cordova International Airport and Enrique Olaya Herrera Airport and arrive at Tocumen International Airport and Marcos A. Gelabert International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Medellín

MDE
Colombia
About the cityHow to get thereWeatherAll about the country Colombia
Arrival

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Departure airports
Arrival airports

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Frequently asked questions about the Medellín — Panama City flight

How long is the flight from Medellín to Panama City?

A nonstop Medellín — Panama City flight takes about 1 h 26 min — the distance between the cities is around 531 km.

How far is it from Medellín to Panama City?

The distance from Medellín to Panama City is about 531 km, which a nonstop flight covers in around 1 h 26 min.

Are there direct flights from Medellín to Panama City?

Yes, there are nonstop flights Medellín — Panama City — around 147 flights per week.

Which airlines fly from Medellín to Panama City?

Airlines operating Medellín — Panama City include Copa Airlines. See the full list with schedules in the "Airlines" section on this page.

Which airports do Medellín — Panama City flights use?

Flights from Medellín depart from Jose Maria Cordova International Airport, Enrique Olaya Herrera Airport, and arrive at Tocumen International Airport, Marcos A. Gelabert International Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Medellín to Panama City?

The price of a Medellín — Panama City ticket depends on your travel date, season and demand: it is usually cheapest to fly in March, and most expensive in November. Tickets typically cost between $164 and $186. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Medellín — Panama City?

Flights Medellín — Panama City are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is March. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Medellín to Panama City?

To catch a low fare Medellín — Panama City, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually March.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from Medellín

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BogotaCartagenaCaliSanta MartaPereiraBarranquillaSan AndresMiamiMonteriaBucaramangaFort LauderdaleLimaSan JoséCúcutaMexico CityArmeniaPunta CanaOrlandoNew York CitySan JuanMadridSanto DomingoCancunQuitoSan SalvadorBuenos AiresRiohachaPastoHoustonGuayaquilWillemstadSantiagoTorontoOranjestad

Where else you can fly from Panama City

See all
BogotaSan JoséMiamiPunta CanaMexico CityNew York CityLimaOrlandoQuitoCancunBuenos AiresSantiagoGuayaquilGuatemala CitySao PauloSanto DomingoSan SalvadorCordobaCaliCartagenaWashington, D.C.Los AngelesHavanaChicagoHoustonRio de JaneiroCaracasMontevideoDavidAsunciónManaguaSan JuanTorontoWillemstadTegucigalpaOranjestadAtlantaMadridPereiraTampa

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