Cheap flights from Panama City to Guayaquil

Tocumen
PTY
José Joaquín de Olmedo
GYE

Flight deals from Panama City to Guayaquil

Below you can see the best deals on flights Panama City — Guayaquil for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 30 September, from $185.

Top 10 cheap flights from Panama City to Guayaquil

CM
$ 239

Panama City — Guayaquil

09:08—11:21
5 Sep 2026
2 h 13 m
Direct flight
CM
$ 239

Panama City — Guayaquil

11:21—13:34
5 Sep 2026
2 h 13 m
Direct flight
CM
$ 239

Panama City — Guayaquil

21:48—00:01
5 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

09:08—11:22
22 Aug 2026
2 h 14 m
Direct flight
CM
$ 240

Panama City — Guayaquil

11:21—13:34
10 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

09:08—11:21
10 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

21:48—00:01
10 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

18:39—20:52
10 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

21:48—00:01
8 Sep 2026
2 h 13 m
Direct flight
CM
$ 240

Panama City — Guayaquil

09:08—11:21
8 Sep 2026
2 h 13 m
Direct flight

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Panama City — Guayaquil flight

Looking for cheap flights from Panama City to Guayaquil? Compare fares from different airlines, check the flight schedule and travel time — and book your Panama City — Guayaquil ticket online at the best price.

The route has direct flights — around 80 flights per week, flights are operated by Copa Airlines, a nonstop flight takes about 2 h 14 min, the distance between the cities is around 1,236 km.

Planning your trip? You may find our Guayaquil travel guide, how to get from the airport into town and Guayaquil weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $185Min. price
SeptemberCheapest
AprilPeak season
YesDirect flights
1,236 kmDistance
2 h 14 minTravel time
1Airlines
80 / wkFlights

Flight schedule from Panama City to Guayaquil

The table shows direct flights from Panama City to Guayaquil on the selected date. The flight takes approximately 2 h 14 min. Regular flights are operated by Copa Airlines. Departures from Tocumen International Airport and Marcos A. Gelabert International Airport airports, arrivals at Jose Joaquin de Olmedo Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 14 Aug 2026

Flight ticket prices by day: Panama City — Guayaquil

Below is a calendar of the lowest flight ticket prices for Panama City — Guayaquil by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $185 in September, and the most expensive are around $257 in April. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Panama City to Guayaquil by month. Tickets are usually cheapest in February (around $228) and priciest in July (about $300) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$264mediumMay$240lowSep$270medium
Feb$228lowJun$288highOct$240low
Mar$252mediumJul$300highNov$246low
Apr$234lowAug$294highDec$300high

Some values are estimated based on seasonality.

When to fly

Weather in Guayaquil: it is warmest in December (up to 30 °C on average) and coolest in June (around 28 °C). The driest month is November.

Tickets are usually cheapest in September and most expensive in April. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Guayaquil

Dry and wet days · Guayaquil

Wind speed and direction · Guayaquil

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How to get the best deal on a Panama City — Guayaquil ticket

  • Book ahead: fares for Panama City — Guayaquil are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Panama City is served by more than one airport — compare fares and travel time to each before you book.
  • The cheapest month to fly to Guayaquil is usually September — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Panama City — Guayaquil route are operated by 1 airline; Copa Airlines runs the most flights (around 100% of all flights). Compare carriers, flight shares and schedules below.

  • Copa AirlinesCM
    27x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight PTY → GYE27x/week
      Duration
      2h 14m
      Days
      MTWTFSS
    100.0%Open →

Cities and airports on the Panama City — Guayaquil route

Flights Panama City — Guayaquil depart from Tocumen International Airport and Marcos A. Gelabert International Airport and arrive at Jose Joaquin de Olmedo Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Arrival

Guayaquil

GYE
Ecuador
About the cityHow to get thereWeatherAll about the country Ecuador
Departure airports
Arrival airports

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Frequently asked questions about the Panama City — Guayaquil flight

How long is the flight from Panama City to Guayaquil?

A nonstop Panama City — Guayaquil flight takes about 2 h 14 min — the distance between the cities is around 1,236 km.

How far is it from Panama City to Guayaquil?

The distance from Panama City to Guayaquil is about 1,236 km, which a nonstop flight covers in around 2 h 14 min.

Are there direct flights from Panama City to Guayaquil?

Yes, there are nonstop flights Panama City — Guayaquil — around 80 flights per week.

Which airlines fly from Panama City to Guayaquil?

Airlines operating Panama City — Guayaquil include Copa Airlines. See the full list with schedules in the "Airlines" section on this page.

Which airports do Panama City — Guayaquil flights use?

Flights from Panama City depart from Tocumen International Airport, Marcos A. Gelabert International Airport, and arrive at Jose Joaquin de Olmedo Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Panama City to Guayaquil?

The price of a Panama City — Guayaquil ticket depends on your travel date, season and demand: it is usually cheapest to fly in September, and most expensive in April. Tickets typically cost between $185 and $257. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Panama City — Guayaquil?

Flights Panama City — Guayaquil are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is September. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Panama City to Guayaquil?

To catch a low fare Panama City — Guayaquil, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually September.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

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