Cheap flights from Guayaquil to Santiago

José Joaquín de Olmedo
GYE
Arturo Merino Benítez
SCL

Flight deals from Guayaquil to Santiago

Below you can see the best deals on flights Guayaquil — Santiago for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 23 September, from $178.

Top 10 cheap flights from Guayaquil to Santiago

LA
LA
$ 198

Guayaquil — Santiago

20:45—05:40
10 Sep 2026
6 h 55 m
1 stop
LA
LA
$ 198

Guayaquil — Santiago

20:45—06:25
10 Sep 2026
7 h 40 m
1 stop
LA
LA
$ 210

Guayaquil — Santiago

09:00—18:25
9 Sep 2026
7 h 25 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

09:00—18:25
13 Sep 2026
7 h 25 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

20:45—06:25
13 Sep 2026
7 h 40 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

20:45—06:45
13 Sep 2026
8 h
1 stop
LA
LA
$ 214

Guayaquil — Santiago

09:00—21:55
13 Sep 2026
10 h 55 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

20:45—15:00
13 Sep 2026
16 h 15 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

09:00—04:25
13 Sep 2026
17 h 25 m
1 stop
LA
LA
$ 214

Guayaquil — Santiago

20:45—04:40
1 Sep 2026
6 h 55 m
1 stop

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Guayaquil — Santiago flight

Looking for cheap flights from Guayaquil to Santiago? Compare fares from different airlines, check the flight schedule and travel time — and book your Guayaquil — Santiago ticket online at the best price.

The route has direct flights — around 14 flights per week, flights are operated by Latam Airlines Group, a nonstop flight takes about 4 h 51 min, the distance between the cities is around 3,592 km.

Planning your trip? You may find our Santiago travel guide, how to get from the airport into town and Santiago weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $178Min. price
SeptemberCheapest
MarchPeak season
YesDirect flights
3,592 kmDistance
4 h 51 minTravel time
1Airlines
14 / wkFlights

Flight schedule from Guayaquil to Santiago

The table shows direct flights from Guayaquil to Santiago on the selected date. The flight takes approximately 4 h 51 min. Regular flights are operated by Latam Airlines Group. Departures from Jose Joaquin de Olmedo Airport airports, arrivals at Arturo Merino Benitez Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 14 Aug 2026

Flight ticket prices by day: Guayaquil — Santiago

Below is a calendar of the lowest flight ticket prices for Guayaquil — Santiago by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $178 in September, and the most expensive are around $297 in March. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Guayaquil to Santiago by month. Tickets are usually cheapest in July (around $348) and priciest in December (about $468) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$456highMay$372lowSep$408high
Feb$444highJun$360lowOct$396medium
Mar$408mediumJul$348lowNov$408medium
Apr$396mediumAug$372mediumDec$468high

Some values are estimated based on seasonality.

When to fly

Weather in Santiago: it is warmest in February (up to 28 °C on average) and coolest in June (around 14 °C). The driest month is December.

Tickets are usually cheapest in September and most expensive in March. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Santiago

Dry and wet days · Santiago

Wind speed and direction · Santiago

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How to get the best deal on a Guayaquil — Santiago ticket

  • Book ahead: fares for Guayaquil — Santiago are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • The cheapest month to fly to Santiago is usually September — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Guayaquil — Santiago route are operated by 1 airline; Latam Airlines Group runs the most flights (around 100% of all flights). Compare carriers, flight shares and schedules below.

  • Latam Airlines GroupLA
    5x/week
    WebsiteFleet: 34782M pax/year
    • Direct flight GYE → SCL5x/week
      Duration
      4h 51m
      Days
      MTWTFSS
    100.0%Open →

Cities and airports on the Guayaquil — Santiago route

Flights Guayaquil — Santiago depart from Jose Joaquin de Olmedo Airport and arrive at Arturo Merino Benitez Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Guayaquil

GYE
Ecuador
About the cityHow to get thereWeatherAll about the country Ecuador
Arrival

Santiago

SCL
Chile
About the cityHow to get thereWeatherAll about the country Chile
Departure airports
Arrival airports

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Frequently asked questions about the Guayaquil — Santiago flight

How long is the flight from Guayaquil to Santiago?

A nonstop Guayaquil — Santiago flight takes about 4 h 51 min — the distance between the cities is around 3,592 km.

How far is it from Guayaquil to Santiago?

The distance from Guayaquil to Santiago is about 3,592 km, which a nonstop flight covers in around 4 h 51 min.

Are there direct flights from Guayaquil to Santiago?

Yes, there are nonstop flights Guayaquil — Santiago — around 14 flights per week.

Which airlines fly from Guayaquil to Santiago?

Airlines operating Guayaquil — Santiago include Latam Airlines Group. See the full list with schedules in the "Airlines" section on this page.

Which airports do Guayaquil — Santiago flights use?

Flights from Guayaquil depart from Jose Joaquin de Olmedo Airport, and arrive at Arturo Merino Benitez Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Guayaquil to Santiago?

The price of a Guayaquil — Santiago ticket depends on your travel date, season and demand: it is usually cheapest to fly in September, and most expensive in March. Tickets typically cost between $178 and $297. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Guayaquil — Santiago?

Flights Guayaquil — Santiago are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is September. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Guayaquil to Santiago?

To catch a low fare Guayaquil — Santiago, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually September.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from Guayaquil

See all
QuitoBogotaPanama CityNew York CityMiamiLimaMadridPuerto AyoraFort LauderdaleMedellínCuencaSan SalvadorBuenos AiresSan CristobalSan JoséAmsterdam

Where else you can fly from Santiago

See all
Buenos AiresCalamaAntofagastaLimaSao PauloConcepciónPuerto MonttLa SerenaRio de JaneiroIquiqueBogotaCopiapoPunta ArenasPanama CityMadridFlorianopolisAricaTemucoMendozaMiamiBalmacedaMontevideoMexico CityHanga RoaSydneyOsornoHoustonBarilocheCuscoBelo HorizonteBrasiliaDallasAtlantaLos AngelesTorontoNew York CityCordobaParisBarcelonaMelbourne

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