Cheap flights from Santa Cruz de la Sierra

El Trompillo
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The main transportation hub of Santa Cruz de la Sierra is Viru Viru International Airport, located 18 kilometers from the city center. From here, 15 key destinations are available, including frequent connections to cities such as Cochabamba (232 flights per week), La Paz (209 flights), and Sucre (81 flights). To better prepare for your trip, we recommend checking the current weather in the region before your departure.

Eight airlines provide air services, with Boliviana de Aviacion being the largest operator. A significant portion of flights are also operated by Gol Transportes Aereos and Copa Airlines, connecting the city with major Latin American hubs. For easy route planning, destination cards are presented below, which you can sort using special filters based on your preferences.

Recent deals from Santa Cruz de la Sierra

OB
$ 82

Santa Cruz de la Sierra — Sucre

10:4511:30
6 Sep 2026
45 m
Direct flight
OB
$ 92

Santa Cruz de la Sierra — Cochabamba

23:5500:40
22 Sep 2026
45 m
Direct flight
OB
OB
$ 116

Santa Cruz de la Sierra — Tarija

05:3508:25
2 Sep 2026
2 h 50 m
1 stop
OB
$ 120

Santa Cruz de la Sierra — La Paz

21:1022:15
25 Aug 2026
1 h 5 m
Direct flight
OB
OB
$ 133

Santa Cruz de la Sierra — Oruro

10:1514:25
17 Sep 2026
4 h 10 m
1 stop
AR
$ 206

Santa Cruz de la Sierra — Buenos Aires

02:2006:20
22 Sep 2026
3 h
Direct flight
OB
$ 210

Santa Cruz de la Sierra — Asunción

13:3016:10
22 Sep 2026
1 h 40 m
Direct flight
G3
$ 220

Santa Cruz de la Sierra — Sao Paulo

12:1515:55
18 Sep 2026
2 h 40 m
Direct flight
OB
$ 227

Santa Cruz de la Sierra — Santiago

21:1501:30
18 Sep 2026
3 h 15 m
Direct flight
OB
$ 249

Santa Cruz de la Sierra — Iquique

14:0516:55
12 Sep 2026
1 h 50 m
Direct flight
OB
$ 257

Santa Cruz de la Sierra — Rio de Janeiro

13:2017:20
30 Aug 2026
3 h
Direct flight
OB
$ 270

Santa Cruz de la Sierra — Lima

20:0021:30
2 Sep 2026
2 h 30 m
Direct flight

Flight insights from Santa Cruz de la Sierra

Data-driven trends for direct flights from Santa Cruz de la Sierra — how often airlines fly, where they go, and typical fares and flight times.

Most frequent destinations

The most frequent direct destinations from Santa Cruz de la Sierra are Cochabamba, La Paz and Sucre. Cochabamba leads with around 232 flights a week.

Top countries

Most direct flights from Santa Cruz de la Sierra head to Bolivia, Brazil and Argentina. Bolivia alone accounts for about 70% of all direct routes.

  • Boliviaavg $99
  • Brazilavg $222
  • Argentinaavg $204
  • Peruavg $240
  • Paraguayavg $210

Direct routes & fares

Popular non-stop routes from Santa Cruz de la Sierra range from Sucre at $61 to Buenos Aires at $204 — a quick way to compare direct-flight fares.

Cheapest destinations

The cheapest destinations from Santa Cruz de la Sierra right now are Sucre from $61, Cochabamba from $78 and La Paz from $109.

Longest direct flights

The longest direct flight from Santa Cruz de la Sierra is to Barcelona at about 12h 32m, followed by Madrid (11h 55m) and New York City (8h 56m).

Popular destinations from Santa Cruz de la Sierra

CochabambaBolivia
Cochabamba
232 flights/weekFrom $ 78
La PazBolivia
La Paz
209 flights/weekFrom $ 109
SucreBolivia
Sucre
81 flights/weekFrom $ 61
Sao PauloBrazil
Sao Paulo
50 flights/weekFrom $ 202
Buenos AiresArgentina
Buenos Aires
32 flights/weekFrom $ 204
TarijaBolivia
Tarija
32 flights/weekFrom $ 116
LimaPeru
Lima
28 flights/weekFrom $ 240
AsunciónParaguay
Asunción
22 flights/weekFrom $ 210
Panama CityPanama
Panama City
22 flights/weekFrom $ 414
MiamiUnited States
Miami
20 flights/weekFrom $ 394
MadridSpain
Madrid
18 flights/weekFrom $ 590
SantiagoChile
Santiago
15 flights/weekFrom $ 227
BogotaColombia
Bogota
14 flights/weekFrom $ 306
Rio de JaneiroBrazil
Rio de Janeiro
10 flights/weekFrom $ 242
IquiqueChile
Iquique
5 flights/weekFrom $ 249
CaracasVenezuela
Caracas
4 flights/weekFrom $ 361
BarcelonaSpain
Barcelona
3 flights/weekFrom $ 696
OruroBolivia
Oruro
2 flights/weekFrom $ 133
Washington, D.C.United States
Washington, D.C.
1 flights/weekFrom $ 468
CuscoPeru
Cusco
From $ 289
SaltaArgentina
Salta
From $ 252
CuritibaBrazil
Curitiba
Check price
ArequipaPeru
Arequipa
Check price
San Miguel de TucumánArgentina
San Miguel de Tucumán
Check price
Foz do IguaçuBrazil
Foz do Iguaçu
Check price
San Salvador de JujuyArgentina
San Salvador de Jujuy
Check price
CordobaArgentina
Cordoba
Check price
CuiabáBrazil
Cuiabá
Check price
Campo GrandeBrazil
Campo Grande
Check price
GoianiaBrazil
Goiania
Check price
TacnaPeru
Tacna
Check price
FlorianopolisBrazil
Florianopolis
Check price
Belo HorizonteBrazil
Belo Horizonte
Check price
Ribeirão PretoBrazil
Ribeirão Preto
Check price
BrasiliaBrazil
Brasilia
Check price
Porto AlegreBrazil
Porto Alegre
Check price
FortalezaBrazil
Fortaleza
From $ 324
CascavelBrazil
Cascavel
Check price
AntofagastaChile
Antofagasta
Check price
Caxias do SulBrazil
Caxias do Sul
Check price
GuayaquilEcuador
Guayaquil
From $ 404
MaringaBrazil
Maringa
Check price
New York CityUnited States
New York City
From $ 505
LondrinaBrazil
Londrina
Check price
ResistenciaArgentina
Resistencia
Check price
Santiago del EsteroArgentina
Santiago del Estero
Check price
TrujilloPeru
Trujillo
Check price
MontevideoUruguay
Montevideo
From $ 293
FormosaArgentina
Formosa
Check price
PosadasArgentina
Posadas
Check price
CorrientesArgentina
Corrientes
Check price
SalvadorBrazil
Salvador
Check price
ManausBrazil
Manaus
From $ 424
RecifeBrazil
Recife
Check price
AyacuchoPeru
Ayacucho
Check price
BelémBrazil
Belém
Check price
UberabaBrazil
Uberaba
Check price
MedellínColombia
Medellín
From $ 317
Presidente PrudenteBrazil
Presidente Prudente
Check price
Porto VelhoBrazil
Porto Velho
Check price
See all destinations from Santa Cruz de la Sierra

Frequently asked questions

How many destinations are available from Santa Cruz de la Sierra?
Currently, there is regular air service to 15 key destinations from the city. The route network includes both domestic flights within Bolivia and international departures to major cities in South and North America, as well as Europe.
What are the most popular destinations from Santa Cruz de la Sierra?
Domestic flights to Cochabamba (232 flights per week) and La Paz (209 flights) are in the highest demand. Among international routes, São Paulo in Brazil leads with a frequency of 50 departures per week, followed by Buenos Aires in Argentina, with 32 weekly flights.
How many airlines fly from Santa Cruz de la Sierra?
Eight airlines operate flights from the city. The largest carrier is Boliviana de Aviacion, and other companies such as Gol Transportes Aereos, Copa Airlines, and Latam Airlines Group also actively serve the airport.
Which airports serve Santa Cruz de la Sierra?
The primary hub for both international and domestic flights is Viru Viru International Airport (VVI). It is located approximately 18 kilometers from the city center and serves as the main air gateway to the region.
How can I find cheap flights from Santa Cruz de la Sierra?
To find the best deals, it is recommended to book your tickets in advance, at least a few months before departure. It is also worth considering mid-week flights and using the filters on our page to compare options from various air carriers.

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