Cheap flights from Santa Cruz de la Sierra to Santiago

El Trompillo
SRZ
Arturo Merino Benítez
SCL

Flight deals from Santa Cruz de la Sierra to Santiago

Below you can see the best deals on flights Santa Cruz de la Sierra — Santiago for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 25 September, from $234.

Top 10 cheap flights from Santa Cruz de la Sierra to Santiago

OB
$ 246

Santa Cruz de la Sierra — Santiago

21:15—00:30
1 Sep 2026
3 h 15 m
Direct flight
OB
$ 246

Santa Cruz de la Sierra — Santiago

21:15—00:30
21 Aug 2026
3 h 15 m
Direct flight
OB
$ 246

Santa Cruz de la Sierra — Santiago

21:15—01:30
8 Sep 2026
3 h 15 m
Direct flight
OB
$ 251

Santa Cruz de la Sierra — Santiago

21:15—00:30
18 Aug 2026
3 h 15 m
Direct flight
OB
$ 271

Santa Cruz de la Sierra — Santiago

21:15—00:30
4 Sep 2026
3 h 15 m
Direct flight
OB
$ 271

Santa Cruz de la Sierra — Santiago

21:15—00:30
28 Aug 2026
3 h 15 m
Direct flight
OB
$ 271

Santa Cruz de la Sierra — Santiago

21:15—01:30
11 Sep 2026
3 h 15 m
Direct flight
AR
AR
$ 274

Santa Cruz de la Sierra — Santiago

02:20—16:35
5 Sep 2026
14 h 15 m
1 stop
AR
AR
$ 276

Santa Cruz de la Sierra — Santiago

02:20—19:45
1 Sep 2026
17 h 25 m
1 stop
AR
AR
$ 276

Santa Cruz de la Sierra — Santiago

02:20—17:20
29 Aug 2026
15 h
1 stop

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Santa Cruz de la Sierra — Santiago flight

Looking for cheap flights from Santa Cruz de la Sierra to Santiago? Compare fares from different airlines, check the flight schedule and travel time — and book your Santa Cruz de la Sierra — Santiago ticket online at the best price.

The route has direct flights — around 15 flights per week, flights are operated by Boliviana de Aviacion, Latam Airlines Group, a nonstop flight takes about 3 h 9 min, the distance between the cities is around 1,888 km.

Planning your trip? You may find our Santiago travel guide, how to get from the airport into town and Santiago weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $234Min. price
SeptemberCheapest
JanuaryPeak season
YesDirect flights
1,888 kmDistance
3 h 9 minTravel time
2Airlines
15 / wkFlights

Flight schedule from Santa Cruz de la Sierra to Santiago

The table shows direct flights from Santa Cruz de la Sierra to Santiago on the selected date. The flight takes approximately 3 h 9 min. Regular flights are operated by Boliviana de Aviacion and Latam Airlines Group. Departures from Viru Viru International Airport airports, arrivals at Arturo Merino Benitez Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 15 Aug 2026

Flight ticket prices by day: Santa Cruz de la Sierra — Santiago

Below is a calendar of the lowest flight ticket prices for Santa Cruz de la Sierra — Santiago by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $234 in September, and the most expensive are around $293 in January. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Santa Cruz de la Sierra to Santiago by month. Tickets are usually cheapest in May (around $228) and priciest in December (about $336) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$324highMay$228lowSep$276medium
Feb$312highJun$240lowOct$264medium
Mar$276mediumJul$324highNov$276medium
Apr$240lowAug$252lowDec$336high

Some values are estimated based on seasonality.

When to fly

Weather in Santiago: it is warmest in February (up to 28 °C on average) and coolest in June (around 14 °C). The driest month is December.

Tickets are usually cheapest in September and most expensive in January. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Santiago

Dry and wet days · Santiago

Wind speed and direction · Santiago

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How to get the best deal on a Santa Cruz de la Sierra — Santiago ticket

  • Book ahead: fares for Santa Cruz de la Sierra — Santiago are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • The cheapest month to fly to Santiago is usually September — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Santa Cruz de la Sierra — Santiago route are operated by 2 airlines; Boliviana de Aviacion runs the most flights (around 73% of all flights). Compare carriers, flight shares and schedules below.

  • Boliviana de AviacionOB
    4x/week
    WebsiteFleet: 204M pax/year
    • Direct flight VVI → SCL4x/week
      Duration
      3h 15m
      Days
      MTWTFSS
    73.3%Open →
  • Latam Airlines GroupLA
    1x/week
    WebsiteFleet: 34782M pax/year
    • Direct flight VVI → SCL1x/week
      Duration
      3h 9m
      Days
      MTWTFSS
    26.7%Open →

Cities and airports on the Santa Cruz de la Sierra — Santiago route

Flights Santa Cruz de la Sierra — Santiago depart from Viru Viru International Airport and arrive at Arturo Merino Benitez Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Santa Cruz de la Sierra

SRZ
Bolivia
About the cityHow to get thereWeatherAll about the country Bolivia
Arrival

Santiago

SCL
Chile
About the cityHow to get thereWeatherAll about the country Chile
Departure airports
Arrival airports

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Frequently asked questions about the Santa Cruz de la Sierra — Santiago flight

How long is the flight from Santa Cruz de la Sierra to Santiago?

A nonstop Santa Cruz de la Sierra — Santiago flight takes about 3 h 9 min — the distance between the cities is around 1,888 km.

How far is it from Santa Cruz de la Sierra to Santiago?

The distance from Santa Cruz de la Sierra to Santiago is about 1,888 km, which a nonstop flight covers in around 3 h 9 min.

Are there direct flights from Santa Cruz de la Sierra to Santiago?

Yes, there are nonstop flights Santa Cruz de la Sierra — Santiago — around 15 flights per week.

Which airlines fly from Santa Cruz de la Sierra to Santiago?

Airlines operating Santa Cruz de la Sierra — Santiago include Boliviana de Aviacion, Latam Airlines Group. See the full list with schedules in the "Airlines" section on this page.

Which airports do Santa Cruz de la Sierra — Santiago flights use?

Flights from Santa Cruz de la Sierra depart from Viru Viru International Airport, and arrive at Arturo Merino Benitez Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Santa Cruz de la Sierra to Santiago?

The price of a Santa Cruz de la Sierra — Santiago ticket depends on your travel date, season and demand: it is usually cheapest to fly in September, and most expensive in January. Tickets typically cost between $234 and $293. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Santa Cruz de la Sierra — Santiago?

Flights Santa Cruz de la Sierra — Santiago are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is September. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Santa Cruz de la Sierra to Santiago?

To catch a low fare Santa Cruz de la Sierra — Santiago, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually September.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from Santa Cruz de la Sierra

See all
CochabambaLa PazSucreSao PauloBuenos AiresTarijaLimaPanama CityAsunciónMiamiMadridBogotaRio de JaneiroIquiqueCaracasBarcelonaOruroWashington, D.C.

Where else you can fly from Santiago

See all
Buenos AiresCalamaAntofagastaLimaSao PauloConcepciónPuerto MonttLa SerenaRio de JaneiroIquiqueBogotaCopiapoPunta ArenasPanama CityMadridFlorianopolisAricaTemucoMendozaMiamiBalmacedaMontevideoMexico CityHanga RoaSydneyOsornoHoustonBarilocheCuscoBelo HorizonteBrasiliaDallasAtlantaLos AngelesNew York CityTorontoCordobaParisGuayaquilBarcelona

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