Cheap flights from Mexico City to Panama City

Benito Juárez
MEX
Tocumen
PTY

Flight deals from Mexico City to Panama City

Below you can see the best deals on flights Mexico City — Panama City for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 25 August, from $182.

Top 10 cheap flights from Mexico City to Panama City

AM
$ 185

Mexico City — Panama City

09:05—14:05
22 Aug 2026
4 h
Direct flight
AM
$ 185

Mexico City — Panama City

09:05—14:05
29 Aug 2026
4 h
Direct flight
AM
$ 187

Mexico City — Panama City

09:05—14:05
25 Aug 2026
4 h
Direct flight
AM
$ 187

Mexico City — Panama City

09:05—14:05
21 Aug 2026
4 h
Direct flight
AM
$ 187

Mexico City — Panama City

09:05—14:05
26 Aug 2026
4 h
Direct flight
AM
$ 187

Mexico City — Panama City

09:05—14:05
30 Aug 2026
4 h
Direct flight
AM
$ 187

Mexico City — Panama City

09:05—14:05
27 Aug 2026
4 h
Direct flight
CM
$ 192

Mexico City — Panama City

02:10—06:51
29 Aug 2026
3 h 41 m
Direct flight
CM
$ 192

Mexico City — Panama City

01:20—06:01
29 Aug 2026
3 h 41 m
Direct flight
CM
$ 192

Mexico City — Panama City

13:10—17:54
29 Aug 2026
3 h 44 m
Direct flight

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Mexico City — Panama City flight

Looking for cheap flights from Mexico City to Panama City? Compare fares from different airlines, check the flight schedule and travel time — and book your Mexico City — Panama City ticket online at the best price.

The route has direct flights — around 103 flights per week, flights are operated by Copa Airlines, Aeromexico, a nonstop flight takes about 3 h 43 min, the distance between the cities is around 2,409 km.

Planning your trip? You may find our Panama City travel guide, how to get from the airport into town and Panama City weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from $182Min. price
AugustCheapest
FebruaryPeak season
YesDirect flights
2,409 kmDistance
3 h 43 minTravel time
2Airlines
103 / wkFlights

Flight schedule from Mexico City to Panama City

The table shows direct flights from Mexico City to Panama City on the selected date. The flight takes approximately 3 h 43 min. Regular flights are operated by Copa Airlines and Aeromexico. Departures from Benito Juarez International Airport, Felipe Angeles International Airport and Toluca International Airport airports, arrivals at Tocumen International Airport and Marcos A. Gelabert International Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 13 Aug 2026

Flight ticket prices by day: Mexico City — Panama City

Below is a calendar of the lowest flight ticket prices for Mexico City — Panama City by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $182 in August, and the most expensive are around $282 in February. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Mexico City to Panama City by month. Tickets are usually cheapest in September (around $218) and priciest in December (about $326) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$314highMay$230lowSep$218low
Feb$290highJun$254mediumOct$218low
Mar$302highJul$290highNov$242medium
Apr$266mediumAug$254mediumDec$326high

Some values are estimated based on seasonality.

When to fly

Weather in Panama City: it is warmest in March (up to 30 °C on average) and coolest in November (around 28 °C). The driest month is February.

Tickets are usually cheapest in August and most expensive in February. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Panama City

Dry and wet days · Panama City

Wind speed and direction · Panama City

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How to get the best deal on a Mexico City — Panama City ticket

  • Book ahead: fares for Mexico City — Panama City are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Mexico City is served by more than one airport — compare fares and travel time to each before you book.
  • The cheapest month to fly to Panama City is usually August — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Mexico City — Panama City route are operated by 2 airlines; Copa Airlines runs the most flights (around 86% of all flights). Compare carriers, flight shares and schedules below.

  • Copa AirlinesCM
    30x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight MEX → PTY30x/week
      Duration
      3h 45m
      Days
      MTWTFSS
    86.4%Open →
  • AeromexicoAM
    5x/week
    WebsiteFleet: 15424.7M pax/year
    • Direct flight MEX → PTY5x/week
      Duration
      4h
      Days
      MTWTFSS
    13.6%Open →

Cities and airports on the Mexico City — Panama City route

Flights Mexico City — Panama City depart from Benito Juarez International Airport, Felipe Angeles International Airport and Toluca International Airport and arrive at Tocumen International Airport and Marcos A. Gelabert International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Mexico City

MEX
Mexico
About the cityHow to get thereWeatherAll about the country Mexico
Arrival

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Departure airports
Arrival airports

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Frequently asked questions about the Mexico City — Panama City flight

How long is the flight from Mexico City to Panama City?

A nonstop Mexico City — Panama City flight takes about 3 h 43 min — the distance between the cities is around 2,409 km.

How far is it from Mexico City to Panama City?

The distance from Mexico City to Panama City is about 2,409 km, which a nonstop flight covers in around 3 h 43 min.

Are there direct flights from Mexico City to Panama City?

Yes, there are nonstop flights Mexico City — Panama City — around 103 flights per week.

Which airlines fly from Mexico City to Panama City?

Airlines operating Mexico City — Panama City include Copa Airlines, Aeromexico. See the full list with schedules in the "Airlines" section on this page.

Which airports do Mexico City — Panama City flights use?

Flights from Mexico City depart from Benito Juarez International Airport, Felipe Angeles International Airport, Toluca International Airport, and arrive at Tocumen International Airport, Marcos A. Gelabert International Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Mexico City to Panama City?

The price of a Mexico City — Panama City ticket depends on your travel date, season and demand: it is usually cheapest to fly in August, and most expensive in February. Tickets typically cost between $182 and $282. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Mexico City — Panama City?

Flights Mexico City — Panama City are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is August. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Mexico City to Panama City?

To catch a low fare Mexico City — Panama City, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually August.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

Where else you can fly from Mexico City

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Where else you can fly from Panama City

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