Cheap flights from Panama City to Mexico City

Tocumen
PTY
Benito Juárez
MEX

Flight deals from Panama City to Mexico City

Below you can see the best deals on flights Panama City — Mexico City for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 7 October, from AED 836.

Top 10 cheap flights from Panama City to Mexico City

CM
Q6
 968

Panama City — Mexico City

21:45—17:50
12 Sep 2026
45 h 5 m
1 stop
CM
Q6
 968

Panama City — Mexico City

10:25—17:50
13 Sep 2026
32 h 25 m
1 stop
CM
Q6
 968

Panama City — Mexico City

08:11—17:50
13 Sep 2026
34 h 39 m
1 stop
CM
Q6
 968

Panama City — Mexico City

07:24—17:50
13 Sep 2026
35 h 26 m
1 stop
CM
Y4
 968

Panama City — Mexico City

08:11—10:30
6 Sep 2026
27 h 19 m
1 stop
CM
Y4
 968

Panama City — Mexico City

07:24—10:30
6 Sep 2026
28 h 6 m
1 stop
CM
Q6
 968

Panama City — Mexico City

08:11—17:50
6 Sep 2026
34 h 39 m
1 stop
CM
Q6
 968

Panama City — Mexico City

07:24—17:50
6 Sep 2026
35 h 26 m
1 stop
CM
Q6
 969

Panama City — Mexico City

10:25—17:50
7 Sep 2026
8 h 25 m
1 stop
CM
Q6
 969

Panama City — Mexico City

08:11—17:50
7 Sep 2026
10 h 39 m
1 stop

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Panama City — Mexico City flight

Looking for cheap flights from Panama City to Mexico City? Compare fares from different airlines, check the flight schedule and travel time — and book your Panama City — Mexico City ticket online at the best price.

The route has direct flights — around 104 flights per week, flights are operated by Copa Airlines, Aeromexico, a nonstop flight takes about 3 h 45 min, the distance between the cities is around 2,409 km.

Planning your trip? You may find our Mexico City travel guide, how to get from the airport into town and Mexico City weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from AED 836Min. price
OctoberCheapest
MayPeak season
YesDirect flights
2,409 kmDistance
3 h 45 minTravel time
2Airlines
104 / wkFlights

Flight schedule from Panama City to Mexico City

The table shows direct flights from Panama City to Mexico City on the selected date. The flight takes approximately 3 h 45 min. Regular flights are operated by Copa Airlines and Aeromexico. Departures from Tocumen International Airport and Marcos A. Gelabert International Airport airports, arrivals at Benito Juarez International Airport, Felipe Angeles International Airport and Toluca International Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 13 Aug 2026

Flight ticket prices by day: Panama City — Mexico City

Below is a calendar of the lowest flight ticket prices for Panama City — Mexico City by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from AED 836 in October, and the most expensive are around AED 1,255 in May. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Panama City to Mexico City by month. Tickets are usually cheapest in March (around AED 802) and priciest in June (about AED 1,229) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
JanAED 976mediumMayAED 1,185highSepAED 846low
FebAED 931mediumJunAED 1,229highOctAED 829low
MarAED 802lowJulAED 1,100highNovAED 976medium
AprAED 976mediumAugAED 976mediumDecAED 1,145high

Some values are estimated based on seasonality.

When to fly

Weather in Mexico City: it is warmest in May (up to 26 °C on average) and coolest in December (around 20 °C). The driest month is January.

Tickets are usually cheapest in October and most expensive in May. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Mexico City

Dry and wet days · Mexico City

Wind speed and direction · Mexico City

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How to get the best deal on a Panama City — Mexico City ticket

  • Book ahead: fares for Panama City — Mexico City are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Panama City is served by more than one airport — compare fares and travel time to each before you book.
  • The cheapest month to fly to Mexico City is usually October — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Panama City — Mexico City route are operated by 2 airlines; Copa Airlines runs the most flights (around 87% of all flights). Compare carriers, flight shares and schedules below.

  • Copa AirlinesCM
    30x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight PTY → MEX30x/week
      Duration
      3h 46m
      Days
      MTWTFSS
    86.5%Open →
  • AeromexicoAM
    5x/week
    WebsiteFleet: 15424.7M pax/year
    • Direct flight PTY → MEX5x/week
      Duration
      3h 53m
      Days
      MTWTFSS
    13.5%Open →

Cities and airports on the Panama City — Mexico City route

Flights Panama City — Mexico City depart from Tocumen International Airport and Marcos A. Gelabert International Airport and arrive at Benito Juarez International Airport, Felipe Angeles International Airport and Toluca International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Arrival

Mexico City

MEX
Mexico
About the cityHow to get thereWeatherAll about the country Mexico
Departure airports
Arrival airports

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Frequently asked questions about the Panama City — Mexico City flight

How long is the flight from Panama City to Mexico City?

A nonstop Panama City — Mexico City flight takes about 3 h 45 min — the distance between the cities is around 2,409 km.

How far is it from Panama City to Mexico City?

The distance from Panama City to Mexico City is about 2,409 km, which a nonstop flight covers in around 3 h 45 min.

Are there direct flights from Panama City to Mexico City?

Yes, there are nonstop flights Panama City — Mexico City — around 104 flights per week.

Which airlines fly from Panama City to Mexico City?

Airlines operating Panama City — Mexico City include Copa Airlines, Aeromexico. See the full list with schedules in the "Airlines" section on this page.

Which airports do Panama City — Mexico City flights use?

Flights from Panama City depart from Tocumen International Airport, Marcos A. Gelabert International Airport, and arrive at Benito Juarez International Airport, Felipe Angeles International Airport, Toluca International Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Panama City to Mexico City?

The price of a Panama City — Mexico City ticket depends on your travel date, season and demand: it is usually cheapest to fly in October, and most expensive in May. Tickets typically cost between AED 836 and AED 1,255. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Panama City — Mexico City?

Flights Panama City — Mexico City are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is October. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Panama City to Mexico City?

To catch a low fare Panama City — Mexico City, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually October.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

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