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Cheap flights from Madrid to Panama City

Madrid
MAD
Panama City
PTY

Flight deals from Madrid to Panama City

Below you can see the best deals on flights Madrid — Panama City for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 9 September, from $390.

Top 10 cheap flights from Madrid to Panama City

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AV
AV
$ 336

Madrid — Panama City

11:05—00:35
1 Sep 2026
12 h 5 m
1 stop
AV
AV
$ 348

Madrid — Panama City

20:05—10:30
23 Aug 2026
13 h 20 m
1 stop
AV
AV
$ 357

Madrid — Panama City

02:10—01:55
3 Sep 2026
13 h 20 m
1 stop
AV
AV
$ 357

Madrid — Panama City

20:05—01:55
30 Aug 2026
13 h 20 m
1 stop
AV
AV
$ 357

Madrid — Panama City

20:05—01:55
23 Aug 2026
13 h 20 m
1 stop
AV
AV
$ 366

Madrid — Panama City

08:10—14:15
26 Aug 2026
12 h 5 m
1 stop
AV
AV
$ 366

Madrid — Panama City

08:10—17:00
26 Aug 2026
12 h 5 m
1 stop
AV
AV
$ 423

Madrid — Panama City

11:05—00:35
2 Sep 2026
12 h 5 m
1 stop
AV
AV
$ 423

Madrid — Panama City

08:10—14:15
27 Aug 2026
12 h 5 m
1 stop
AV
AV
$ 423

Madrid — Panama City

11:05—00:35
27 Aug 2026
12 h 5 m
1 stop
View all

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Madrid — Panama City flight

On this page, you can find and buy flight tickets for the Madrid — Panama City route. The 8,169 km flight between Spain and Panama is serviced regularly, with a traffic intensity of about 10 flights per week. Detailed logistics information can be found in the sections on how to get to Madrid airport and transport from Panama City airport.

Airlines such as IB, UX, and CM operate on this route. The cost of a flight depends on many factors, so we recommend using the low-price calendar and the price dynamics chart provided on this page to find the most advantageous offers.

Flight ticket prices by day: Madrid — Panama City

Below is a calendar of the lowest flight ticket prices for Madrid — Panama City by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from $388 in u, and the most expensive are around $577 in r. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Madrid → Panama City, average one-way price

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
Jan$1,159highMay$982mediumSep$932low
Feb$1,133highJun$1,008mediumOct$907low
Mar$1,108highJul$1,133highNov$982medium
Apr$1,033mediumAug$1,159highDec$1,184high

Some values are estimated based on seasonality.

When to fly

The weather in Panama City is characterized by consistently high temperatures, reaching a maximum of 30.1°C in March and April. The rainiest month is July, with up to 346 mm of precipitation, while the driest period falls in February.

The lowest ticket prices are recorded in September, starting $360. Prices peak in December, when the cost of travel increases to $556 due to high seasonal demand.

April is considered the optimal time for a trip, with prices starting $388, as it combines moderate prices with the end of the dry season. Those wishing to minimize the number of rainy days should avoid the period from July to November.

Temperature · Panama City

Dry and wet days · Panama City

Wind speed and direction · Panama City

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How to get the best deal on a Madrid — Panama City ticket

  • Book your flight tickets 2–3 months in advance, as prices for transatlantic flights increase significantly as the departure date approaches.
  • Compare direct Iberia flights with options that include layovers: sometimes connecting routes allow you to find tickets $360.
  • Use the low-price calendar on this page to check the cost of flights on nearby dates — shifting your departure by 1–2 days can significantly reduce your expenses.
  • Check the baggage rules of your chosen airline, as on a route spanning 8,169 km, the fee for an extra suitcase at the airport can exceed the savings from a cheap fare.

Airlines

There are 6 airlines operating on this route, with Iberia and Air Europa being the main carriers. Direct flights and convenient connections provide a flight frequency of up to 10 times per week. You can review the detailed schedule and choose the most suitable route option in the interactive list below.

  • Air EuropaUX
    5x/week
    WebsiteFleet: 5011.5M pax/year
    • Direct flight MAD → PTY5x/week
    46.7%Open →
  • IberiaIB
    4x/week
    WebsiteFleet: 9224M pax/year
    • Direct flight MAD → PTY4x/week
      Duration
      11h 5m
      Days
      MTWTFSS
    40.0%Open →
  • Copa AirlinesCM
    1x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight MAD → PTY1x/week
    3.3%Open →
  • EtihadEY
    1x/week
    WebsiteFleet: 9714M pax/year
    • Direct flight MAD → PTY1x/week
    3.3%Open →
  • Hainan AirlinesHU
    1x/week
    WebsiteFleet: 22457M pax/year
    • Direct flight MAD → PTY1x/week
    3.3%Open →
  • China EasternMU
    1x/week
    WebsiteFleet: 803116M pax/year
    • Direct flight MAD → PTY1x/week
    3.3%Open →

Cities and airports on the Madrid — Panama City route

Flights Madrid — Panama City depart from Adolfo Suárez Madrid-Barajas Airport and arrive at Tocumen International Airport and Marcos A. Gelabert International Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Madrid

MAD
Spain
About the cityHow to get thereWeatherAll about the country Spain
Arrival

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Departure airports
Arrival airports

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Frequently asked questions about the Madrid — Panama City flight

How long is the flight from Madrid to Panama City?

A direct flight covering a distance of 8,169 km takes approximately 10–11 hours. Travel time for flights with layovers depends on the chosen route and the duration of the connection.

Which airlines fly on this route?

Regular air service is provided by companies such as Iberia, Air Europa, Copa Airlines, and Etihad Airways. A full list of carriers is available on this page.

Are there direct flights from Madrid to Panama City?

Yes, there are regular direct flights on this route, allowing you to reach your destination as quickly as possible without any transfers.

Which airport does the flight arrive at?

Most international flights from Spain arrive at Panama City's main airport — Tocumen (PTY).

How can I find the cheapest ticket?

Ticket prices are constantly changing. To find the best deal, we recommend monitoring the price chart and the low-price calendar provided above.

Where else you can fly from Madrid

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Santa Cruz de TenerifeLondonParisPalmaLisbonBarcelonaLas PalmasRomeIbizaMilanAmsterdamMunichPortoBilbaoFrankfurt am MainMalagaBrusselsVigoNew York CityGenevaA CoruñaZurichBogotaOviedoSevilleAlicanteVeniceArrecifeValenciaSao PauloIstanbulAthensMahonDusseldorfLimaBerlinCasablancaBuenos AiresCopenhagenTel Aviv

Where else you can fly from Panama City

See all
BogotaMedellínSan JoséMiamiPunta CanaMexico CityNew York CityLimaOrlandoCancunQuitoBuenos AiresSantiagoGuayaquilGuatemala CitySao PauloSanto DomingoSan SalvadorCordobaCaliCartagenaWashington, D.C.Los AngelesChicagoHavanaCaracasDavidHoustonMontevideoRio de JaneiroAsunciónManaguaSan JuanTorontoWillemstadTegucigalpaAtlantaOranjestadPereiraBocas del Toro

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