Cheap flights from Panama City to Santiago

Tocumen
PTY
Arturo Merino Benítez
SCL

Flight deals from Panama City to Santiago

Below you can see the best deals on flights Panama City — Santiago for upcoming dates. Direct and connecting flights from various airlines — compare prices and choose the right ticket.

The lowest price for the next 2 months is on 13 August, from AED 1,396.

Top 10 cheap flights from Panama City to Santiago

AV
AV
 1,441

Panama City — Santiago

04:25—14:15
31 Aug 2026
8 h 50 m
1 stop
AV
AV
 1,441

Panama City — Santiago

17:55—04:45
31 Aug 2026
9 h 50 m
1 stop
AV
AV
 1,441

Panama City — Santiago

10:10—23:20
31 Aug 2026
12 h 10 m
1 stop
AV
AV
 1,441

Panama City — Santiago

15:10—04:45
31 Aug 2026
12 h 35 m
1 stop
AV
AV
 1,441

Panama City — Santiago

10:10—04:45
31 Aug 2026
17 h 35 m
1 stop
AV
AV
 1,441

Panama City — Santiago

04:25—23:20
31 Aug 2026
17 h 55 m
1 stop
AV
AV
 1,441

Panama City — Santiago

17:55—14:15
31 Aug 2026
19 h 20 m
1 stop
AV
AV
 1,441

Panama City — Santiago

15:10—14:15
31 Aug 2026
22 h 5 m
1 stop
AV
AV
 1,441

Panama City — Santiago

04:25—04:45
31 Aug 2026
23 h 20 m
1 stop
AV
AV
 1,441

Panama City — Santiago

10:10—14:15
31 Aug 2026
27 h 5 m
1 stop

Prices were found in the last 72 hours and may change — check the exact price when you continue.

About the Panama City — Santiago flight

Looking for cheap flights from Panama City to Santiago? Compare fares from different airlines, check the flight schedule and travel time — and book your Panama City — Santiago ticket online at the best price.

The route has direct flights — around 82 flights per week, flights are operated by Copa Airlines, a nonstop flight takes about 6 h 35 min, the distance between the cities is around 4,788 km.

Planning your trip? You may find our Santiago travel guide, how to get from the airport into town and Santiago weather forecast useful. To catch a low fare, use the low-price calendar and the monthly price chart on this page.

Facts about this route

from AED 1,201Min. price
OctoberCheapest
SeptemberPeak season
YesDirect flights
4,788 kmDistance
6 h 35 minTravel time
1Airlines
82 / wkFlights

Flight schedule from Panama City to Santiago

The table shows direct flights from Panama City to Santiago on the selected date. The flight takes approximately 6 h 35 min. Regular flights are operated by Copa Airlines. Departures from Tocumen International Airport and Marcos A. Gelabert International Airport airports, arrivals at Arturo Merino Benitez Airport.

For each flight, the following details are shown: departure time (local), arrival city and airport, flight number and airline, terminal or gate, and status. Click on a flight to open its details and go to ticket search. To view flights on a different day, change the date above the table.

Today
Any time
Last update: 13 Aug 2026

Flight ticket prices by day: Panama City — Santiago

Below is a calendar of the lowest flight ticket prices for Panama City — Santiago by day. Pick a convenient date and instantly see the fare. The cheapest flights on this route start from AED 1,201 in October, and the most expensive are around AED 1,434 in September. If your travel dates are flexible, the calendar will help you find the best price for your preferred period. To view round-trip fares, switch to the "Round trip" tab above the calendar, select your departure date — and the right-hand calendar will highlight the lowest prices for return flights on each day.

 
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Prices by month

Average one-way fares from Panama City to Santiago by month. Tickets are usually cheapest in June (around AED 1,871) and priciest in January (about AED 2,895) — use the table and chart below to pick the best time to fly.

MonthAverage priceLevelMonthAverage priceLevelMonthAverage priceLevel
JanAED 2,895highMayAED 1,960lowSepAED 2,183medium
FebAED 2,762highJunAED 1,871lowOctAED 2,138medium
MarAED 2,316mediumJulAED 2,138mediumNovAED 2,227medium
AprAED 2,227mediumAugAED 1,915lowDecAED 2,851high

Some values are estimated based on seasonality.

When to fly

Weather in Santiago: it is warmest in February (up to 28 °C on average) and coolest in June (around 14 °C). The driest month is December.

Tickets are usually cheapest in October and most expensive in September. Compare prices and weather by month in the charts below to pick the best time to fly.

Temperature · Santiago

Dry and wet days · Santiago

Wind speed and direction · Santiago

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How to get the best deal on a Panama City — Santiago ticket

  • Book ahead: fares for Panama City — Santiago are usually lower 3–8 weeks before departure than at the last minute.
  • Play with your dates — Tuesday, Wednesday and Saturday departures are often cheaper than Friday and Sunday.
  • Panama City is served by more than one airport — compare fares and travel time to each before you book.
  • The cheapest month to fly to Santiago is usually October — plan your trip around it if your dates are flexible.
  • Compare direct and connecting flights: nonstop is faster, while a connection is sometimes noticeably cheaper.
  • Watch the low-price calendar and the monthly price trend on this page — they make it easier to catch a good date.
  • Travelling light? Pick a cabin-baggage-only fare — tickets without checked luggage are noticeably cheaper.
  • Get to the airport in good time — about 2–3 hours before an international departure and roughly an hour before a domestic one.

Airlines

Flights on the Panama City — Santiago route are operated by 1 airline; Copa Airlines runs the most flights (around 100% of all flights). Compare carriers, flight shares and schedules below.

  • Copa AirlinesCM
    27x/week
    WebsiteFleet: 10316.1M pax/year
    • Direct flight PTY → SCL27x/week
      Duration
      6h 35m
      Days
      MTWTFSS
    100.0%Open →

Cities and airports on the Panama City — Santiago route

Flights Panama City — Santiago depart from Tocumen International Airport and Marcos A. Gelabert International Airport and arrive at Arturo Merino Benitez Airport. Below are pages for the cities, countries, and airports on the route: airlines, schedules, and travel guides.

Departure

Panama City

PTY
Panama
About the cityHow to get thereWeatherAll about the country Panama
Arrival

Santiago

SCL
Chile
About the cityHow to get thereWeatherAll about the country Chile
Departure airports
Arrival airports

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Frequently asked questions about the Panama City — Santiago flight

How long is the flight from Panama City to Santiago?

A nonstop Panama City — Santiago flight takes about 6 h 35 min — the distance between the cities is around 4,788 km.

How far is it from Panama City to Santiago?

The distance from Panama City to Santiago is about 4,788 km, which a nonstop flight covers in around 6 h 35 min.

Are there direct flights from Panama City to Santiago?

Yes, there are nonstop flights Panama City — Santiago — around 82 flights per week.

Which airlines fly from Panama City to Santiago?

Airlines operating Panama City — Santiago include Copa Airlines. See the full list with schedules in the "Airlines" section on this page.

Which airports do Panama City — Santiago flights use?

Flights from Panama City depart from Tocumen International Airport, Marcos A. Gelabert International Airport, and arrive at Arturo Merino Benitez Airport. If a city has more than one airport, check which one your ticket uses before you travel.

How much is a ticket from Panama City to Santiago?

The price of a Panama City — Santiago ticket depends on your travel date, season and demand: it is usually cheapest to fly in October, and most expensive in September. Tickets typically cost between AED 1,201 and AED 1,434. Check the current lowest fare and low-price calendar on this page.

When is the best time to book flights Panama City — Santiago?

Flights Panama City — Santiago are usually cheaper when booked in advance — a few weeks before departure and away from peak dates; the most budget-friendly month to fly is October. Compare prices by month in the price trend chart on this page.

How can I find the cheapest flights from Panama City to Santiago?

To catch a low fare Panama City — Santiago, book a few weeks in advance, keep your dates flexible, and compare airlines and connecting options. The low-price calendar and monthly price chart on this page show the cheapest days and months at a glance: the most budget-friendly month to fly is usually October.

How early should I arrive at the airport?

For international flights, plan to be at the airport about 2–3 hours before departure, and around an hour before a domestic flight. Allow extra time during busy travel seasons and at large hubs, where check-in and security lines can be longer.

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Where else you can fly from Santiago

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